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Sudden unexpected death in epilepsy (SUDEP) refers to unpredictable demise of a person following a seizure. Electroencephalograms can directly measure electrical activity in the brain; however, it cannot predict when seizures will occur. The use of electrocardiograms (ECGs) to monitor changes in brain electrical activity has gained attention, recently. In this case report, we retrospectively reviewed ECGs taken before and after seizure activity in a 75-year-old male who had a remote subarachnoid hemorrhage. Interestingly, U-waves appeared prior to his seizures and disappeared afterward, which suggests ECGs can be used to predict epilepsy in a certain population.
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http://dx.doi.org/10.1111/anec.70014 | DOI Listing |
BMJ Open
August 2025
Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China
Introduction: A large number of basic and clinical studies have demonstrated that remote ischaemic conditioning (RIC) has neuroprotective effects. Recently, RIC has made gratifying progress in the field of ischaemia stroke treatment. A considerable number of basic and clinical studies have also revealed the possible therapeutic effects of RIC on subarachnoid haemorrhage.
View Article and Find Full Text PDFClin Case Rep
July 2025
Biomedical and Experimental Department, Faculty of Medicine University of Medicine in Tirana Tirana Albania.
The diagnosis of a subarachnoid hemorrhage is challenging, and has important clinical, therapeutic and prognostic implications. Delayed NPMSAH (non-aneurysmal perimesencephalic SAH) may involve subtle venous injury, aberrant venous anatomy or increased intracranial venous pressure. In all "idiopathic" cases, a remote traumatic event should be considered, and approached accordingly.
View Article and Find Full Text PDFNeurocrit Care
July 2025
Department of Neurosurgery, TUM School of Medicine and Health, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Background: Remote ischemic preconditioning (RIPC) has shown potential in reducing vasospasm-induced secondary ischemia after aneurysmal subarachnoid hemorrhage (aSAH). Research suggests RIPC may help the brain adapt to periods of reduced blood flow, thereby reducing the risk of cerebral infarction secondary to delayed cerebral ischemia. This study aimed to analyze the possible impact of RIPC in patients with vasospasm following aSAH.
View Article and Find Full Text PDFJ Clin Neurosci
August 2025
Faculty of Medicine, University of Queensland, Herston, QLD, Australia; Townsville University Hospital, Douglas, QLD, Australia. Electronic address:
Background: Aneurysmal subarachnoid haemorrhage (aSAH) is a life-threatening condition that demands prompt neurosurgical intervention. In Australia, the vast geographic distances and the substantial proportion of the population living in rural or remote areas may hinder access to timely care, potentially influencing patient outcomes. Although medical retrieval services are well-established and regional centres provide primary care, patients with aSAH in remote areas may experience poorer outcomes compared to those in urban centres.
View Article and Find Full Text PDFJ Patient Cent Res Rev
April 2025
Commonwealth Serum Laboratories (CSL) Behring, King of Prussia, PA.
Aneurysmal subarachnoid hemorrhage (aSAH) is characterized by a high rate of fatality and high risk of secondary brain injury. More treatment options are needed to improve outcomes. There are very few reports in the medical literature involving patient experience of aSAH, which is known for its unexpected onset and profound medical impact.
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