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http://dx.doi.org/10.12669/pjms.40.8.9779 | DOI Listing |
Front Psychiatry
August 2025
Neuropsychiatry Department, Okasha Institute of Psychiatry, Ain Shams University, Cairo, Egypt.
Background: Methamphetamine use disorder (MUD) is linked to a variety of cognitive and neuropsychiatric deficits. One of the illegal substances that is most frequently abused is cannabis. The general consensus is that both recreational cannabis and methamphetamine use result in a wide spectrum of severe cognitive impairments, although there have been questions raised regarding conclusions derived from published material.
View Article and Find Full Text PDFWorld J Hepatol
August 2025
Storr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Sydney 2145, New South Wales, Australia.
Metabolic dysfunction-associated fatty liver disease (MAFLD) now affects roughly one-quarter of the world's population, reflecting the global spread of obesity and insulin resistance. Reframing non-alcoholic fatty liver disease as MAFLD emphasizes its metabolic roots and spotlights the gut-liver axis, where intestinal dysbiosis acts as a key driver of hepatic injury. Altered microbial communities disrupt epithelial integrity, promote bacterial translocation, and trigger endotoxin-mediated inflammation that accelerates steatosis, lipotoxicity, and fibrogenesis.
View Article and Find Full Text PDFPhlebology
September 2025
Emeritus Professor of Venous Surgery, Rotterdam, Netherlands.
BackgroundCompression therapy (CT) is widely prescribed for chronic venous disease (CVD), lymphedema, and lipedema despite robust evidence supporting its effectiveness only in a minority of clinical scenarios.AimProvide an overview of the methodological parameters essential for obtaining a high-quality scientific trial.MethodsThe International Compression Club (ICC) chairman prepared a preliminary list of the main methodological flaws in publications on CT, and a list of parameters to be included in high-quality randomized controlled trials (RCTs).
View Article and Find Full Text PDFJ Hosp Infect
August 2025
Infection Prevention and Control Unit and Hub, Department of Integrated Health Services, World Health Organization (WHO), Geneva, Switzerland.
Background: The World Health Organization (WHO) recently developed the global action plan (GAP) and monitoring framework (MF) for Infection Prevention and Control (IPC). An e-Delphi survey was conducted as part of a consultative process to achieve consensus on IPC MF indicators and targets.
Methods: The study was conducted as an e-Delphi consensus-seeking exercise, with two rounds of sequential surveys.
JMIR Res Protoc
August 2025
Institute of Global Health and Human Ecology, American University in Cairo, New Cairo, Egypt.
Background: Marked by high mortality rates on a global scale, with disease mortality being notably focused among older adults, the COVID-19 pandemic has become a significant health crisis. Despite the numerous publications on COVID-19 mortality among older adults, there is still a gap in knowledge when considering centenarians, as there is no systematic review and meta-analysis that summarizes COVID-19 mortality in centenarians globally.
Objective: This study aims to systematically review and synthesize global evidence on COVID-19 mortality rates among centenarians and the population of older adults worldwide, whether residing in long-term health facilities, hospitals, or their homes.