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| http://dx.doi.org/10.1016/j.celrep.2024.114754 | DOI Listing |
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Background: Malaria is one of the most infectious diseases, and electrolyte imbalance and mineral disturbances are common clinical manifestations. This study aimed to explore the effect of malaria on biochemical parameters in Sudanese patients with severe falciparum malaria.
Methods: A case-control study was conducted in the clinical laboratory of the Kosti Teaching Hospital between August 2022 and January 2023.
Impact of NLRP1 Met1154Val and IL1B variants on gestational malaria: an unexplored role of NLRP1 in inflammasome activation by Plasmodium spp.
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Departamento de Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo (ICB/USP), São Paulo, Brazil.
We hypothesized that variants in inflammasome-related genes could influence susceptibility to gestational malaria (GM). To test this, we conducted an association study in a cohort of pregnant women from a malaria-endemic region in northern Brazil, assessing whether specific functional single nucleotide variants (SNVs) in inflammasome genes affect (1) the response to Plasmodium infection and (2) the development of placental malaria. Our findings revealed that the NLRP1 p.
View Article and Find Full Text PDFAcute kidney injury is one of the most severe complications of severe malaria, with an overall incidence reaching 60% and a mortality rate of up to 45%. We conducted this study to determine the prevalence of acute kidney injury in malaria, acute kidney injury, associated factors and the impact of acute kidney injury on vital prognosis. This was a multicenter, retrospective, descriptive, and analytical study over a 5-year period from January 1, 2019 to December 31, 2023, in the nephrology and infectious diseases departments and intensive care units of Dakar hospitals.
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African Leaders Malaria Alliance, New York, USA.
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View Article and Find Full Text PDFHuman Blood Index of in Ethiopia: A Systematic Review and Meta-Analysis.
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Department of Biology, Debre Markos University, Debre Markos, Ethiopia.
, the primary malaria vector in Ethiopia, exhibits diverse feeding behaviors influenced by geography, climate, and control strategies. Understanding its blood-feeding preference is crucial for devising effective interventions. This study aimed to conduct a systematic review and meta-analysis of existing evidence on human blood index (HBI) in Ethiopia.
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