98%
921
2 minutes
20
Hymenopteran insect stings are a risk factor that cannot be ignored for the people allergic to hymenopteran venoms.In China,the current diagnostic tools cannot provide accurate information to identify sensitized insects,thus affecting clinical diagnosis and treatment.Honeybee is a common hymenopteran insect.Due to its wide distribution,large number,and complex venom composition,researchers have carried out recombination schemes for the main allergens of honeybee venom,laying a theoretical foundation for the detection of allergens.The development of diagnostic technologies for allergen components can accurately detect bee venom allergens,providing a new set of clinical diagnosis and treatment schemes for the population allergic to bee venom.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.3881/j.issn.1000-503X.15770 | DOI Listing |
Front Toxicol
August 2025
One Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.
Background: Each year, approximately 100 million cases of bee and wasp stings are re-ported globally, with the majority resulting in mild reactions. However, in rarer instances, these stings can lead to severe and potentially fatal outcomes, including ischemic or hemorrhagic cerebral events. This article aims to synthesize and analyze the current evidence on the association between bee and wasp stings and the occurrence of ischemic and hemorrhagic strokes.
View Article and Find Full Text PDFToxicon
September 2025
Department of Toxicology and Forensic medicine, Faulty of Veterinary Medicine, Cairo University, Giza 11221, Egypt. Electronic address:
Bee venom and its principal peptide, melittin, are natural compounds with many therapeutic effects. They are also known for their hemolytic and cytotoxic properties that render their medical applications. Poly lactic-co-glycolic acid (PLGA) is a popular polymer used for different drug delivery.
View Article and Find Full Text PDFIntegr Med Res
March 2026
Department of Acupuncture and Moxibustion Medicine, Pusan National University Korean Medicine Hospital, Yangsan, Republic of Korea.
Background: In the clinical practice of Korean Medicine, pharmacopuncture therapy and acupotomy (PA) are being increasingly explored as potential treatment options for degenerative lumbar spinal stenosis (LSS). In this study, we aimed to evaluate the effectiveness and safety of combining PA with conventional Korean Medicine treatment (CKMT) in patients with degenerative LSS.
Methods: A pragmatic, assessor-blinded, randomized controlled trial was conducted with 104 participants aged 40-75 years diagnosed with degenerative LSS.
Pediatr Allergy Immunol
September 2025
Allergy Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
Background: Hymenoptera venom allergy is a significant cause of morbidity and mortality, also in pediatric patients, highlighting the importance of effective management through venom immunotherapy (VIT). This study aimed to evaluate the safety profile of VIT, identify factors associated with adverse reactions (ARs), assess the accuracy of insect identification and its impact on VIT extract selection, and determine treatment efficacy by analyzing ARs following re-sting.
Methods: The medical charts of patients followed up at the Allergy Unit of Meyer Children's Hospital IRCCS, Florence, Italy, who completed a VIT cycle between 1997 and 2021 were retrospectively analyzed.
J Pept Sci
October 2025
Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
The development of novel candidate molecules for breast cancer treatment holds significant clinical value. Panurgines (PNG), derived from the venom of the wild bee Panurgus calcaratus, are particularly noteworthy for their anti-breast cancer activity and antibacterial properties. However, linear peptides are often hindered by poor stability and limited cell membrane permeability, making them highly susceptible to protease degradation.
View Article and Find Full Text PDF