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Obesity in Heart Failure with Reduced Ejection Fraction: Time to Address the Elephant in the Room. | LitMetric

Obesity in Heart Failure with Reduced Ejection Fraction: Time to Address the Elephant in the Room.

Heart Fail Clin

Department of Cardiovascular Diseases, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, USA; University Hospitals Medical Center, Cleveland, OH, USA. Electronic address:

Published: October 2024


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Article Abstract

Obesity has been long recognized as a risk factor for the development of heart failure, but recent evidence suggests obesity is more typically associated with heart failure with preserved ejection fraction as opposed to heart failure with reduced ejection fraction (HFrEF). Nevertheless, numerous studies have found that obesity modulates the presentation and progression of HFrEF and may contribute to the development of HFrEF in some patients. Although obesity has definite negative effects in HFrEF patients, the effects of intentional weight loss in HFrEF patients with obesity have been poorly studied.

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Source
http://dx.doi.org/10.1016/j.hfc.2024.06.006DOI Listing

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