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Prostatitis is one of the three most common prostate diseases in men, the other two being prostatic hyperplasia and prostate cancer, and about 50% of men worldwide have been attacked by prostatitis during their lives. The incidence of infertility is significantly higher in patients with chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS) than in those without it, which is mainly attributed to the changed semen composition of the CP/CPPS patients. Using the key words chronic prostatitis, chronic pelvic pain syndrome, sperm, semen, and seminal plasma, we searched PubMed and Medical Lines online for originals, review articles, clinical trials, case reports and associated citations on humans and animals published up to 2024. We comprehensively reviewed the previous studies and investigations relating chronic prostatitis, seminal plasma change and sperm quality, and discussed the impact of the change of semen composition on sperm quality.
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Pain Manag
September 2025
Serviço de Reabilitação de Adultos 3, Centro de Medicina de Reabilitação de Alcoitão, Alcabideche, Portugal.
Pudendal neuropathy is a cause of pelvic pain, specifically pudendal neuralgia. The pudendal nerve is related to sensory, motor, and autonomic functions. We present the case of a 41-year-old man who suffered from chronic pelvic pain.
View Article and Find Full Text PDFCancer Biol Med
September 2025
Department of Urology, First Affiliated Hospital of Jiujiang Medical University, Jiujiang 332000, China.
Prostate cancer is a significant global health issue with inflammation emerging as a critical driver of progression. The prostate tumor microenvironment (TME) is comprised of tumor cells, mesenchymal stem cells, immune cells, cancer-associated fibroblasts, adipocytes, and the extracellular matrix. All of these TME components interact soluble factors, such as growth factors, cytokines, and chemokines.
View Article and Find Full Text PDFArch Esp Urol
August 2025
Department of Urology, The First People's Hospital of Jiujiang, 332000 Jiujiang, Jiangxi, China.
Background: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent urological condition affecting men's health. This study aims to investigate the clinical efficacy of Qianlie Shutong (QLST) capsule in the treatment of CP/CPPS.
Methods: The medical records of patients with CP/CPPS who were admitted to our hospital from January 2023 to January 2024 were retrospectively analysed.
J Environ Pathol Toxicol Oncol
September 2025
Department of Biostatistics, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Prostate cancer and inflammation mechanism are closely related because chronic inflammation causes inflammatory cells to infiltrate into prostatic atrophy areas and proliferative inflammatory atrophy is accepted as the initiator of prostate cancer. The study included 90 patients (28 patients with benign prostatic hyperplasia (BPH), 35 patients with localized prostate cancer (LPCa), and 27 patients with metastatic prostate cancer (MPCa) and 90 healthy controls. Blood samples from 90 patients and 90 healthy people were used to isolate genomic DNA.
View Article and Find Full Text PDFCRSLS
September 2025
Faculty of Medicine, Department of Internal Medicine, Division of Intensive Care Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Türkiye. (Dr. Demirer Aydemir).
We present a rare morphological variant of a colonic polyp observed during a routine screening colonoscopy. A 62-year-old male with known chronic obstructive pulmonary disease (COPD) and benign prostatic hyperplasia (BPH) was found to have a bridge-shaped polyp in the sigmoid colon. The polyp was successfully resected via snare polypectomy following submucosal adrenaline injection.
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