98%
921
2 minutes
20
False-positive ctDNA results do not explain lack of efficacy for PARPi in patients with ATMm and CHEK2m CRPC.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11371381 | PMC |
http://dx.doi.org/10.1200/PO.24.00354 | DOI Listing |
Sci Adv
September 2025
Sol Price School of Public Policy, University of Southern California, Los Angeles, CA, USA.
Antimicrobial resistance is largely driven by overuse of antibiotics, which is particularly common in low- and middle-income countries. We combine provider knowledge assessments and over 2000 anonymous standardized patient visits to providers in India to examine why they overprescribe antibiotics for pediatric diarrhea and figure out how to reduce overprescribing. Seventy percent of providers prescribed antibiotics without indication of bacterial infection.
View Article and Find Full Text PDFSmall
September 2025
Nanochemistry Department, Max Planck Institute for Solid State Research, Heisenbergstraße 1, 70569, Stuttgart, Germany.
Flexible metal-organic frameworks (MOFs) have emerged as a new generation of porous materials and are considered for various applications such as sensing, water or gas capture, and water purification. MIL-88 A (Fe) is one of the earliest and most researched flexible MOFs, but to date, there is a lack in the structural aspects that govern its dynamic behaviour. Here, we report the first crystal structure of DMF-solvated MIL-88 A and investigate the impact of real structure effects on the dynamic behaviour of MIL-88 A (Fe), particularly upon water adsorption.
View Article and Find Full Text PDFCancer Med
September 2025
Department of Computer Engineering, Social and Biological Network Analysis Laboratory, University of Kurdistan, Sanandaj, Iran.
Background: Ovarian cancer (OC) remains the most lethal gynecological malignancy, largely due to its late-stage diagnosis and nonspecific early symptoms. Advances in biomarker identification and machine learning offer promising avenues for improving early detection and prognosis. This review evaluates the role of biomarker-driven ML models in enhancing the early detection, risk stratification, and treatment planning of OC.
View Article and Find Full Text PDFFront Nutr
August 2025
Thaer-Institute-Div. Urban Plant Ecophysiology, Humboldt-Universität zu Berlin, Berlin, Germany.
Background: Changes in consumer food choices have been associated with transformation in the food environment. Despite the direct impact of consumers' food choices on their diet and health outcomes, there is a lack of comprehensive evidence regarding how various factors within the food environment impact these choices.
Methods: This study uses the Theory of Planned Behavior to examine how socio-psychological factors in the food environment influence consumers' healthy food choices.
Alpha Psychiatry
August 2025
Department of Psychiatry, Bakirkoy Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, 34147 Istanbul, Turkey.
Objective: In bipolar disorder, residual mood symptoms often persist even during the euthymic period, impairing functionality in 30-60% of patients in clinical remission. Addressing residual symptoms is critical as they are linked to reduced functionality and subjective wellbeing. This cross-sectional study aimed to determine the relationship between mindful attention awareness (MASS) and residual symptom severity in bipolar I disorder.
View Article and Find Full Text PDF