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The information-seeking behaviour of adults focuses on optimizing the gathering and utilizing information to minimize search costs. In contrast, children tend to engage in information search during decision-making with less consideration for costs. This difference in behaviour is believed to be linked to the development of executive functions. Therefore, the present study aimed to investigate the relationship between executive function and cost-related information-gathering behaviour. We assessed 56 children aged 4-6 years, involving three tasks: an information-gathering task, an inhibitory control and a working memory task. In the information-gathering task, children participated in both non-cost and cost conditions, where they were given the opportunity to freely gather information or incur a cost to acquire information. The findings revealed that children with higher inhibitory control tended to gather less information when a cost was involved. This highlights the important role of inhibitory control in shaping information-seeking behaviour in early childhood.
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http://dx.doi.org/10.1111/bjdp.12518 | DOI Listing |
J Sleep Res
September 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Kansai Medical University, Hirakata, Japan.
In obstructive sleep apnea (OSA), repeated airway obstruction alters mucosal inflammation, which increases exhaled nitric oxide (NO) production in the nasal cavity. However, the underlying mechanism remains unclear. Accordingly, we aimed to examine the mechanism underlying NO production in patients with OSA.
View Article and Find Full Text PDFNan Fang Yi Ke Da Xue Xue Bao
August 2025
College of Laboratory Medicine, Wannan Medical College, Wuhu 241000, China.
Objectives: To investigate the role of circular RNA circ_0000437 in regulating biological behaviors of breast cancer cells and the molecular mechanism.
Methods: Breast cancer MCF-7 and MDA-MB-231 cells were transfected with sh-circ_0000437, mimics, inhibitor, si-CTPS1, or their respective negative controls. qRT-PCR was used to detect the expression levels of circ_0000437, let-7b-5p, CTPS1, Notch1, Hes1, and Numb in breast cancer cell lines and tissues.
Nan Fang Yi Ke Da Xue Xue Bao
August 2025
Department of Nursing, Shenzhen Hospital, Southern Medical University, Shenzhen 518101, China.
Objectives: To investigate the therapeutic effect of acupuncture in a rat model of insomnia and its regulatory effect on the glutamic acid (Glu)/γ-aminobutyric acid (GABA)-glutamine (Gln) metabolic loop.
Methods: Forty male SD rats were randomly assigned to control group, model group, group and group (=10). In the latter 3 groups, rat models of insomnia were established by intraperitoneal injections of p-chlorophenylalanine and verified using a sodium pentobarbital-induced sleep test.
Turk J Pharm Sci
September 2025
İstanbul University Faculty of Pharmacy, Department of Pharmaceutical Chemistry, İstanbul, Türkiye.
Objectives: This study focused on synthesizing and characterizing novel thiosemicarbazide derivatives containing a 1,2,4-triazole moiety and evaluating their antimicrobial activity against several bacterial strains. The research aimed to identify key structural features that enhance antimicrobial efficacy through structure-activity relationship analysis and identify the minimum inhibitory concentration (MIC) of the most potent compounds to assess their potential for further development as antimicrobial agents.
Materials And Methods: Nine novel thiosemicarbazide derivatives containing a 1,2,4-triazole moiety were synthesized by reacting 1,2,4-triazole derivatives with thiosemicarbazide precursors, and the products were characterized using infrared spectroscopy, proton nuclear magnetic resonance (H-NMR), carbon-13 nuclear magnetic resonance (C-NMR) spectroscopy, and elemental analysis.
Rev Argent Microbiol
September 2025
IPICYT, División de Biología Molecular, Laboratorio de Genómica Funcional y Comparativa, Camino a la Presa San José 2055, Col. Lomas 4 Sección, 78216 San Luis Potosí, SLP, Mexico.
Fungal diseases in agricultural crops cause economic losses, with chemical control being the conventional method to manage them. However, this approach negatively impacts both the environment and human health. This study focused on endophytic fungi isolated from the roots of Ceratozamia mirandae in the Mexican locality of Juan Sabines (Villa Corzo, Chiapas).
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