Similar Publications

The Effect of Rosavin, a Characteristic Compound of , on BMP-2 Induction and Osteoblast Proliferation In Vitro.

Int J Mol Sci

June 2025

Department of Biophysics, Physiology and Pathophysiology, Faculty of Health Sciences, Medical University of Warsaw, 5 Chałubińskiego Street, 02-004 Warsaw, Poland.

Rosavin, a glycoside isolated from , exhibits various biological activities, including potential modulation of metabolic pathways. Despite promising findings in animal models, its effects on many human bone cells remain unexplored. This study aimed to investigate, for the first time, the in vitro effects of rosavin on human osteoblasts (HOBs), focusing on BMP-2 expression, cell morphology, and culture confluence as indicators of osteogenic activity.

View Article and Find Full Text PDF

Inflammation and oxidative stress caused by fine particulate matter (PM2.5) increase the incidence and mortality rates of respiratory disorders. Rosavin is the main chemical component of Rhodiola plants, which exerts anti-oxidative and antiinflammatory effects.

View Article and Find Full Text PDF