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Purpose: Lower extremity chronic exertional compartment syndrome (LE-CECS) can limit rigorous physical activity, particularly in the US military, and fasciotomy is a potential treatment. Associations between LE-CECS, fasciotomy, and occupational outcomes appear understudied. We studied active-duty US service members to identify whether LE-CECS diagnoses and fasciotomy for LE-CECS predict military service separation.
Methods: We conducted a retrospective cohort study of 1,103,417 individuals who entered service during 2011 to 2017. Distributions of separation statuses and independent variables were tabulated, and sex-specific multivariable regression models were computed for separation outcomes.
Results: LE-CECS was associated with a 474% medical service separation risk in men (95% confidence interval (CI) for adjusted risk ratio: 5.21 to 6.33) and a 282% increase in women (CI: 2.99 to 4.88). Among 1947 patients with LE-CECS, men saw a 57% nonmedical separation risk increase (CI: 1.27 to 1.93) and women had a 119% increase (CI: 1.10 to 4.35) when anterior and/or lateral compartment procedures occurred. Men with LE-CECS and any posterior procedures saw a 47% nonmedical separation risk increase (CI: 1.17 to 1.86). Men with anterior and/or lateral procedures and any posterior procedures experienced 36% (CI: 1.09 to 1.71) and 78% (CI: 1.40 to 2.26) medical separation risk increases, respectively. No statistically significant risk increases for the outcomes were otherwise seen for women.
Conclusions: LE-CECS was associated with increased military service discharge risks. Among the affected patients, positive effects on career longevity were not seen in association with fasciotomy. However, fasciotomy could simply serve as a marker of the most refractory cases that are least likely to continue service. More study is needed to clarify causal pathways and identify patients who may derive career benefits from surgical treatment.
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http://dx.doi.org/10.1249/MSS.0000000000003471 | DOI Listing |
Front Surg
August 2025
Department of Epidemiology, The University of Texas Health Science Center School of Public Health, Houston, TX, United States.
Background: Solid organ transplant (SOT) recipients are not only at increased risk of morbidity and mortality due to acute COVID-19 but may also experience poor long-term outcomes due to post-acute COVID-19 syndromes, including long COVID.
Methods: This retrospective, registry-based chart review evaluated graft failure and mortality among SOT recipients diagnosed with COVID-19 at a large, urban transplant center in Houston, Texas, USA. Patient populations were analyzed separately according to their long COVID status at the time of transplant to preserve the temporal relationship between the exposure (long COVID) and the outcome (graft failure or mortality).
J Multidiscip Healthc
September 2025
School of Criminology, People's Public Security University of China, Beijing, People's Republic of China.
Background: Violence against doctors is a common worldwide problem. Such risk events, due to the further exaggeration by media reports, trigger collective anxiety among medical staff. Using structural equation modeling (SEM), this study reveals how media portrayals erode clinician trust through amplified risk perception.
View Article and Find Full Text PDFEnviron Epidemiol
October 2025
Department of Psychiatry and Behavioral Health, The Ohio State University, Ohio.
Background: Prospective studies suggest that prenatal exposure to chemical neurotoxicants and maternal stress increase risk for psychiatric problems. However, most studies have focused on childhood outcomes, leaving adolescence-a critical period for the emergence or worsening of psychiatric symptoms-relatively understudied. The complexity of prenatal coexposures and adolescent psychiatric comorbidities, particularly among structurally marginalized populations with high exposure burdens, remains poorly understood.
View Article and Find Full Text PDFClin Ophthalmol
September 2025
Helen Keller Eye Research Foundation, Birmingham, AL, USA.
Rhegmatogenous retinal detachment (retinal detachment, RD) is the most common cause of spontaneous vision loss in aging eyes that were seeing normally until the moment of its occurrence. Causative retinal breaks usually occur in the form of peripheral tears at the vitreous base, resulting from traction exerted by the aging vitreous as it detaches posteriorly. Peripheral encircling laser retinopexy increases retinal resistance to vitreous traction in high-risk eyes.
View Article and Find Full Text PDFAlpha Psychiatry
August 2025
Center for Studies of Psychological Application, Guangdong Key Laboratory of Mental Health and Cognitive Science, and School of Psychology, South China Normal University, 510631 Guangzhou, Guangdong, China.
Background: Children's mental health is significantly influenced by family environments, where multiple risks often coexist, exert unequal impacts, and combine in different configurations that can result in diverse developmental outcomes. This study examines how different configurations of cumulative family risks influence mental health symptoms in Chinese children using a novel person-centered approach.
Materials And Methods: Data were collected through a large-scale, semester-based comprehensive survey of 34,041 children in Grades 4 to 6 in an economically underdeveloped county-level city in Guangdong, China, during November and December, 2022.