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Objectives: The objective is to assess the interconnectedness of a network of health-related quality of life (HRQoL) variables among people with HIV (PHIV) to identify key areas for which clinical interventions could improve HRQoL for this population.
Methods: Between 2021 and 2023, we carried out a cross-sectional study within the Spanish CoRIS cohort. We conducted a weighted and undirected network analysis, which examines complex patterns of relationships and interconnections between variables, to assess a network of eight HRQoL dimensions from the validated Clinic Screening Tool for HIV (CST-HIV): anticipated stigma, psychological distress, sexuality, social support, material deprivation, sleep and fatigue, cognitive problems and physical symptoms.
Results: A total of 347 participants, predominantly male (93.1%), currently working (79.0%), self-reported homosexual (72.6%) and college-educated (53.9%), were included in the study. Psychological distress showed the highest centrality in the network, indicating its strong connections with sleep and fatigue, cognitive problems and social support within the HRQoL network.
Conclusions: Psychological distress, sleep and fatigue, cognitive issues and social support were identified as key factors in an HRQoL network, indicating that interventions focused on these areas could significantly enhance overall well-being.
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http://dx.doi.org/10.1111/hiv.13693 | DOI Listing |
Am J Clin Hypn
September 2025
Higher Institute of Nursing and Health Technology, Rabat, Morocco.
Gestational trophoblastic tumors (GTTs) encompass a spectrum of neoplastic conditions, including invasive mole, choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor. Invasive mole, which frequently develops following a complete hydatidiform mole, represents the most common form. A cancer diagnosis constitutes a profoundly destabilizing experience, often resulting in considerable psychological distress.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Lübeck, Lübeck, Germany.
Importance: Patients with inflammatory rheumatic diseases (IRDs) frequently experience psychological distress; however, access to psychological support remains limited.
Objective: To investigate the effectiveness of a digital psychological intervention for individuals with IRDs.
Design, Setting, And Participants: Participants aged 18 years or older were recruited across Germany between February 22 and June 4, 2024, if they had been diagnosed with rheumatoid arthritis, psoriatic arthritis, or systemic lupus erythematosus and reported psychological distress and reduced quality of life.
J Neurol
September 2025
Multiple Sclerosis Center, Sheba Medical Center, Derech Sheba 2, Tel Hashomer, Israel.
Introduction: Psychological stress has been proposed as a trigger for disease activity in multiple sclerosis (MS), but findings have been inconsistent. While prior research has focused largely on chronic stressors, little is known about how people with MS (pwMS) cope with acute, large-scale stress events such as war.
Objective: Examine the effects of wartime stress following the October 7, 2023 attack on disease activity in pwMS, and to assess whether emotional factors are associated with relapse risk during this period.
Int J Soc Psychiatry
September 2025
Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Background: Climate distress is a psychological reaction to adverse weather events and climate change. These events can increase people's vulnerability to develop psychiatric disorders like anxiety, depression, and PTSD particularly in disaster-prone regions like India.
Aim: To explore the relationship between climate distress and psychological impact with a particular emphasis on women, elderly, and other at risk populations who owing to their health vulnerabilities, lack of resources or social roles that make them dependent on others, experience stress in the face of climate change.
Cureus
September 2025
Pediatrics, University of Nevada Reno School of Medicine, Reno, USA.
Goldenhar syndrome, a rare congenital condition, often presents with physical anomalies due to abnormal development of the first and second branchial arches, leading to facial and auricular malformations. However, the mental health challenges associated with this syndrome are often overlooked. This report describes the case of a 14-year-old Latino/Hispanic male child with Goldenhar syndrome and limited verbal communication, highlighting the complexities of managing both physical and psychological aspects of care after establishing follow-up with a pediatrician.
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