Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: to map scientific evidence regarding the use of local pressure devices in pain relief during injection procedures in patients.
Methods: scoping review, following the recommendations of the JBI Manual for Evidence Synthesis and PRISMA-ScR, with searches conducted in the PubMed, EMBASE, CINAHL, LILACS, and PsycINFO databases, without temporal restrictions and with a cutoff date of March 2023.
Results: a total of 1,514 studies were identified, with 20 articles included in the final sample. The ShotBlocker® device was utilized during subcutaneous and intramuscular injections in children and adults, proving beneficial in reducing pain, anxiety, and fear associated with the procedure.
Final Considerations: the ShotBlocker® is a low-cost, easy-to-use device that can enhance nursing clinical practice during painful procedures. However, studies involving the Brazilian Pikluc® device are scarce. Further research involving both local pressure devices is recommended.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11290735 | PMC |
| http://dx.doi.org/10.1590/0034-7167-2023-0399 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Macrophage Migratory Inhibitory Factor May Contribute to the Production of Nitric Oxide in Obstructive Sleep Apnea.
J Sleep Res
September 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Kansai Medical University, Hirakata, Japan.
In obstructive sleep apnea (OSA), repeated airway obstruction alters mucosal inflammation, which increases exhaled nitric oxide (NO) production in the nasal cavity. However, the underlying mechanism remains unclear. Accordingly, we aimed to examine the mechanism underlying NO production in patients with OSA.
View Article and Find Full Text PDFThe transcription factor MrbHLH2 significantly affects stress resistance and insect virulence in Metarhizium robertsii.
Fungal Biol
October 2025
Anhui Provincial Key Laboratory of Microbial Pest Control, Anhui Agricultural University, Hefei, 230036, China. Electronic address:
Basic helix-loop-helix (bHLH) transcription factors are essential regulators of various biological processes, including growth, development, and stress responses in eukaryotes. Despite their importance, the specific roles of bHLH factors in entomopathogenic fungi remain inadequately understood. In this study, we identified and characterized the bHLH transcription factor MrbHLH2 in the entomopathogenic fungus Metarhizium robertsii, which is widely used in biological control.
View Article and Find Full Text PDFCo-existence of mcr-1 and bla from porcine-derived Escherichia coli isolated in China and selection of mcr-1 under cephalosporins pressure.
J Glob Antimicrob Resist
September 2025
Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Changchun, Jilin 130122, China. Electronic address:
Objectives: The usage of cephalosporins (CEFs) and co-existence of extended-spectrum β-lactamase (ESBL) gene bla in the same host may promote the prevalence of colistin (CST) resistance gene mcr-1. This study aims to investigate the underlying mechanisms how the mcr-1 and bla demonstrate significant co-occurrence in Escherichia coli (E. coli).
View Article and Find Full Text PDFParoxetine attenuates sepsis by preserving the expression of the G protein-coupled chemokine receptor CXCR2 on neutrophils.
Int Immunopharmacol
September 2025
Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil; Center for Research in Inflammatory Diseases, CRID, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil. Electronic address:
Sepsis, a life-threatening organ dysfunction caused by a dysregulated host response to infection, is associated with impaired neutrophil migration to the infectious focus owing to G protein-coupled receptor kinase (GRK2)-dependent CXCR2 internalization. In the present study, we investigated whether paroxetine, an antidepressant that belongs to the selective serotonin reuptake inhibitor (SSRI) class of drugs and that is also identified as a GRK2 inhibitor, can improve neutrophil recruitment in the cecal ligation and puncture (CLP)-induced sepsis model. Moderate (mCLP) and severe (sCLP) polymicrobial peritonitis were induced in C57BL/6 mice.
View Article and Find Full Text PDFHaemodynamic characteristics of thin-walled regions in intracranial aneurysms: intraoperative imaging and CFD analysis.
Acta Neurochir (Wien)
September 2025
Faculty of Medicine, The University of Queensland, Herston, QLD, 4006, Australia.
Background: Identifying haemodynamic factors associated with thin-walled regions (TWRs) of intracranial aneurysms is critical for improving pre-surgical rupture risk assessment. Intraoperatively, these regions are visually distinguished by a red, translucent appearance and are considered highly rupture prone. However, current imaging modalities lack the resolution to detect such vulnerable areas preoperatively.
View Article and Find Full Text PDF