Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Magnetic resonance imaging is currently used in the neonatal setting for assessing features of the neonatal brain. However, its utilization is constrained by logistic, technical, or clinical challenges. Brain elastography is a new research technique which enhances the diagnostic capability of traditional imaging, and can be paired with both ultrasonography and magnetic resonance imaging. In particular, brain elastography adds objective and quantitative information to traditional imaging by detecting differences in tissue elasticity/stiffness, which may represent a surrogate marker of the physiologic and pathologic features of the neonatal brain. To date, very limited experience exists about the use of brain elastography specifically in the neonatal setting. The aim of the present review was to describe the most recent information about the feasibility and diagnostic accuracy of brain ultrasound elastography (USE) in neonates, and to provide information about the possible future applications and perspectives of brain elastography.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11274596 | PMC |
| http://dx.doi.org/10.3390/children11070752 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
MR Passive Elastography: From Seismic Noise Tomography to Brain Tumors Characterization.
J Magn Reson Imaging
September 2025
Laboratoire D'imagerie biomédicale Multimodales à Paris-Saclay, BioMaps, Université Paris-Saclay, CEA, CNRS UMR 9011, Inserm, Orsay, France.
Impact of the melanocortin-4 receptor agonist setmelanotide on MASLD and kidney function in Bardet-Biedl syndrome.
J Clin Endocrinol Metab
September 2025
Department of Pediatrics II, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Background & Objective: The melanocortin-4 receptor agonist setmelanotide compensates for upstream gene defects in the brain leptin-melanocortin pathway and reduces hyperphagia and obesity in selected monogenic obesity forms and Bardet-Biedl syndrome (BBS). We aimed to evaluate the short-term impact of setmelanotide treatment in BBS presenting original real-world data focusing on metabolic dysfunction-associated steatotic liver disease (MASLD) and kidney function.
Methods: This monocentric, prospective observational cohort study was performed between June and December 2023 and included patients above the age of 6 years with genetically confirmed BBS, obesity and/or hyperphagia and planned setmelanotide therapy.
Histological visualizations of tissues are critical to disease diagnosis. Conventional histopathology requires labor-intensive and time-consuming tissue preparation, leading to diagnostic delays of days or even weeks. Here, we developed a label-free histological imaging method based on a reflection-mode ultraviolet photoacoustic elastography (UV-PAE) and near-infrared optical coherence microscopy (NIR-OCM).
View Article and Find Full Text PDFElevated Plasma BDNF in Early Primary Biliary Cholangitis: Associations with Liver Fibrosis, IL-6, IL-18, Fatigue, and Cognitive Impairment.
Int J Mol Sci
July 2025
Department of Gastroenterology and Internal Medicine, Medical University of Białystok, 15-089 Białystok, Poland.
Background And Aims: Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease frequently associated with fatigue and mild cognitive impairment. Brain-derived neurotrophic factor (BDNF) plays key roles in neuroplasticity, immune regulation, and metabolism. This study aimed to evaluate plasma BDNF levels in early-stage PBC and examine their clinical and biochemical associations.
View Article and Find Full Text PDFAdvances and innovations in ultrasound-based tumor management: current applications and emerging directions.
Ultrasound J
August 2025
Department of Ultrasound, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
As a crucial medical imaging modality, ultrasonography has emerged as a pivotal tool for tumor diagnosis and treatment owing to its non-invasive nature, real-time imaging capability, and superior resolution. Recent technological advancements have demonstrated unique advantages in early tumor screening, staging, and localization. Contrast-enhanced ultrasound (CEUS), utilizing microbubbles (MBs) and nanobubbles (NBs) to target vascular biomarkers, significantly enhances tumor visualization and demonstrates high sensitivity in molecular imaging.
View Article and Find Full Text PDF