Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Locally advanced rectal cancer has historically been treated with multimodal therapy consisting of radiation therapy, chemotherapy, and total mesorectal excision. However, recent prospective trials and registry studies have demonstrated similar disease outcomes with nonoperative management for patients who experience an excellent clinical response to radiation and chemotherapy. This article reviews data regarding nonoperative management for rectal cancer, and highlights current challenges and limitations in a point-counterpoint format, in the context of two clinical cases.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/PPO.0000000000000732 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Poor fracture alignment equals poor outcome? Analysis of conservatively managed distal radius fractures.
Arch Orthop Trauma Surg
September 2025
Orthopaedics and traumatology, Salzburger Landeskliniken, Salzburg, Austria.
Purpose: The NOM (non-operative management) of distal radius fractures (DRF) is influenced by various factors. This study seeks to determine whether poor fracture alignment correlates with poor outcome.
Methods: Over a period of three years, a study was conducted on conservatively treated DRF involving 127 patients, 104 women (81.
Shoulder Instability in Contact and Collision Athletes: A Focused Review on Assessment, Management, and Treatment.
Curr Sports Med Rep
September 2025
Department of Orthopaedics, University of North Carolina School of Medicine, Chapel Hill, NC.
Glenohumeral instability is a common injury affecting contact and collision athletes. Male sex, younger age at time of first dislocation, and contact sports participation are risk factors for recurrent instability. MRI is the gold standard to evaluate soft tissue structures, while CT is beneficial in quantifying glenoid bone loss and identifying on-track and off-track Hill-Sachs lesions.
View Article and Find Full Text PDFAdvances in Nonoperative Management of Osteoarthritis in Athletes.
Curr Sports Med Rep
September 2025
U.S. Army and Department of Family Medicine, F. Edward Hébert School of Medicine, Uniformed Services University, Bethesda, MD.
Osteoarthritis is a leading cause of disability in both the United States and worldwide. In comparison to nonexposed controls, athletes, including tactical athletes such as military members and first responders, have higher rates of osteoarthritis. Management of osteoarthritis in the athletic population is largely similar to management of osteoarthritis in the general population, with a strong emphasis on conservative management.
View Article and Find Full Text PDFPatient-reported outcomes following patella fractures : a nationwide observational study of 8,726 patients from the Swedish Fracture Register.
Bone Jt Open
September 2025
Department of Orthopaedics, Uppsala University, Uppsala, Sweden.
Aims: Patella fractures can greatly impact knee function and quality of life. The primary aim of this study was to assess patient-reported outcomes one-year post-patella fracture. A secondary aim was to evaluate outcome differences based on sex, age, fracture classification, treatment modality, and patients' expectations.
View Article and Find Full Text PDFIntraoperative Pneumatocele Formation during Liver Transplantation for Polycystic Liver Disease: Successful Non-Operative Management.
Surg Case Rep
September 2025
Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kanazawa University, Kanazawa, Ishikawa, Japan.
Introduction: Liver transplantation for polycystic liver disease (PLD) poses significant intraoperative risks due to the presence of a massively enlarged liver. We report a rare case of intraoperative pneumothorax and pneumatocele formation during total hepatectomy, which was successfully managed with a non-operative approach.
Case Presentation: A female patient in her 40s with a history of autosomal dominant polycystic kidney disease presented with progressive liver cyst enlargement (Gigot type III, Qian classification Grade 4), which led to decreased activities of daily living and intracystic hemorrhage.