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COVID-19 mothers' mother-baby bonding, feeding practices, postnatal care experiences in Qatar: A mixed-methods approach.
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Nursing and Midwifery Research Department, Hamad Medical Corporation, Doha, Qatar.
Introduction: The study aim was to examine mother-infant bonding, feeding practices, and postnatal care experiences of mothers diagnosed with COVID-19 in hospital settings from 2020 to 2022.
Methods: A mixed-methods research design was conducted, involving 117 participants in a cross-sectional online survey and 11 phone interviews. The study was conducted among mothers diagnosed with COVID-19 by PCR test and admitted to four maternity facilities in Qatar from 1 May 2020 to 16 January 2022.
Combination therapy with biologics and/or small molecules in inflammatory bowel disease: a comprehensive review.
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Gastroenterology Unit, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-Princesa), Universidad Autónoma de Madrid (UAM), and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain.
Advanced combination treatment (ACT)-the combination of two advanced agents such as biologics or small molecules-has emerged as a promising strategy in the management of inflammatory bowel disease refractory to conventional treatment, with severe extraintestinal manifestations, or with coexisting immune-mediated inflammatory diseases. ACT including complementary mechanisms of action aims to overcome the therapeutic ceiling observed with monotherapy. Its rationale is supported by preclinical and mechanistic data demonstrating synergistic immunological effects when distinct inflammatory pathways are targeted simultaneously.
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Sodium-glucose cotransporter-2 inhibitors (SGLT-2i) have demonstrated renoprotective and cardioprotective benefits beyond their antiglycemic effects. Their potential utility in kidney transplant recipients (KTRs) for preserving graft function and reducing rejection risk is currently under active investigation. Preliminary studies indicate that SGLT-2i therapy stabilizes estimated glomerular filtration rate (eGFR), decreases glomerular hyperfiltration, and improves metabolic outcomes in KTRs.
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: Orchialgia following kidney donation is an underrecognized complication with reported incidence varying dramatically between retrospective (2-3%) and prospective (44-55%) studies, suggesting significant underreporting. This study aimed to determine the incidence, characteristics, and clinical relevance of orchialgia in male kidney donors within 2 years post-donation using direct patient assessment. : This is a cross-sectional study of 100 male donors (64.
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Cureus
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Pediatrics and Neonatology, King Salman Specialized Hospital, Taif, SAU.
Background Meconium aspiration syndrome (MAS) is a critical neonatal condition predominantly associated with term and post-term pregnancies, characterized by the aspiration of meconium-stained amniotic fluid (MSAF) leading to severe respiratory distress. Despite advances in obstetric and neonatal care, MAS remains a significant cause of neonatal morbidity, particularly in settings with limited access to advanced neonatal care. Objectives This study aimed to evaluate the prevalence of mechanical ventilation and explore potential predictors for respiratory support in neonates diagnosed with MAS at King Salman Armed Forces Hospital (KSAFH) in Tabuk, Saudi Arabia, from 2020 to 2024.
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