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Purpose: To compare postoperative complications in women undergoing total hysterectomy with segmental resection (TH-SR) for intestinal endometriosis with or without protective defunctioning stoma (PDS) confection.
Methods: Retrospective cohort study conducted at the Gynecologic department of University Hospital of Lille (France) from January 2008 to January 2022 in patients undergone TH-SR for bowel endometriosis.
Results: 100 women were considered for the analysis. PDS were performed in 56 women. The rate of rectal resections was significantly higher in the PDS group (p = 0.03). The mean operative time, AAGL scores and length of hospital stay were significantly higher in the PDS group (p = 0.002). The rate of grade III complication according to Clavien-Dindo classification was higher in the PDS group (p = 0.03). Among digestive complications, one case of anastomosis leakage (1.8%) and one case of recto-vaginal fistula (2.3%) was recorded in the non-PDS group, 4 cases of anastomosis stenosis were recorded in the PDS group (7.1%). Persisting bladder atony requiring self-catheterization over one month was the most common disturb (4.6% in the non-PDS group and 7.1% in the PDS group, p = 0.58). The distance of digestive lesion from anal margin was the only risk factor for digestive complications, persistent bladder atony, Clavien-Dindo IIIA and IIIB complications at the multivariate analysis (p = 0.04 and p = 0.06 respectively).
Conclusion: No statistically significant differences were found in the rate of digestive complications in case of total hysterectomy and concomitant segmental resection when performing or not preventing stoma.
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http://dx.doi.org/10.1007/s00404-024-07629-5 | DOI Listing |
J Stud Alcohol Drugs
September 2025
National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Background: Historically, cannabis use and cannabis use disorder (CUD) have been more prevalent among males. However, emerging evidence suggests cannabis use may be increasing faster among females in younger age groups. This study characterized changes in female versus male differences in cannabis use and CUD across age groups and time.
View Article and Find Full Text PDFPurpose: The primary purpose was to assess sulcus angle (SA) magnetic resonance imaging (MRI) measurements and determine diagnostic cutoff values along four axial levels on cartilaginous and osseous surfaces comparing those with patellar dislocations (PD) versus controls. A secondary aim was to identify differences in SA between patients with one-time dislocation (OTD) versus recurrent patellar dislocations (RPDs).
Methods: Paediatric patients with a history of PD were retrospectively grouped into those with an OTD versus RPDs.
Hum Psychopharmacol
September 2025
Psychology and Neuroscience, University of Colorado Boulder, Boulder, Colorado, USA.
Objective: This study examined the effects of tetrahydrocannabinol (THC) and cannabidiol (CBD) on negative mood and drinking behaviors, and whether those effects were moderated by levels of perceived discrimination among participants who identify with a racial, ethnic, gender, or sexual identity that is underrepresented in research.
Methods: Participants were either not using cannabis, using cannabis with THC, or using cannabis with CBD and were assessed at baseline, 2 weeks, and 4-weeks following ad libitum use of a legal market cannabis product that was randomly assigned to them. Primary outcomes included scores on the Depression Anxiety Stress (DASS) Scale and number of drinking days.
Eur J Cancer
August 2025
Department of Dermatology, University Hospital Tübingen, Tübingen, Germany. Electronic address:
Introduction: For rare skin cancers, few data exist on the outcome of systemic therapies, particularly immune checkpoint inhibition (ICI). The present study analysed the real-world use of different systemic therapies including ICI, and its outcome in patients with advanced rare skin cancers.
Methods: This retrospective multicenter study included patients who received systemic therapy for advanced, non-resectable cutaneous angiosarcoma (AS), Kaposi sarcoma (KS), pleomorphic dermal sarcoma (PDS), or cutaneous adnexal carcinoma (CAC).
Ann Rehabil Med
August 2025
Medical Department Wojciech Korfanty, Upper Silesian Academy, Katowice, Poland.
Objective: To compare the Hong (GH) and sustained insertion (GS) dry needling methods in patients with myofascial neck pain, this experimental study was conducted.
Methods: A randomized controlled trial included 30 participants, assigned to either the GH (n=15) or GS (n=15) group. Each group received treatment on either the right or left side, with one side receiving experimental DN and the other receiving control (sham) DN.