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Gastrointestinal bleeding due to hemobilia is a rare condition but can be very serious, even life-threatening. The main causes of biliary bleeding are invasive procedures in treatment, trauma, or malignant diseases. Chronic obstruction of the biliary tract can cause inflammation, erosion, and leakage of adjacent vascular structures and lead to pseudoaneurysm or hemorrhage, but this is very rare. In this article, we present a clinical case of upper gastrointestinal bleeding due to a pseudoaneurysm of the hepatic artery believed to have formed due to chronic cholangitis. An 81-year-old female patient with a medical history of chronic cholangitis was admitted to the hospital with recurrent inflammation accompanied by progressive upper gastrointestinal bleeding, potentially life-threatening. Ultrasound images and blood tests confirmed that the patient had anemia and cholangitis caused by stones. Gastrointestinal endoscopy showed bleeding suspected to be from the biliary tract. Hepatobiliary computed tomography confirmed that the common hepatic artery pseudoaneurysm located at the upper end of the common bile duct had active bleeding.
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http://dx.doi.org/10.1016/j.radcr.2024.05.065 | DOI Listing |
Surg Endosc
September 2025
Department of Surgery, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
Background: Endoscopic vacuum therapy (EVT) has been established as a safe and effective treatment for anastomotic leakage. While rare, major aortic hemorrhage has been reported as a severe complication potentially associated with EVT. However, significant hemorrhages have also been observed in patients with transmural defects in the upper gastrointestinal tract, without the use of EVT.
View Article and Find Full Text PDFCureus
August 2025
Internal Medicine, Good Shepherd Hospital, Wayanad, IND.
Heyde's syndrome signifies the link between aortic stenosis (AS) and bleeding due to angiodysplastic changes. While colonic angiodysplasia is commonly implicated, gastric antral vascular ectasia (GAVE) represents a rarer manifestation in this context. We report the case of a 72-year-old male with severe AS who had recurrent upper gastrointestinal bleeding due to GAVE.
View Article and Find Full Text PDFJ Formos Med Assoc
September 2025
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; Health Management Center, National Taiwan University Hospital, Taipei, Taiwan; Endoscopic Division, Department of Integrated Diagnostic & Therapeutics, National Taiwan University Hospital, Taipei, Taiwan.
Background And Purpose: Colonoscopy is an essential diagnostic and therapeutic tool for lower gastrointestinal bleeding (LGIB), with colonoscopic hemostasis needed in a subset of patients. We aim to identify risk factors associated with colonoscopic hemostasis requirement in acute LGIB patients.
Methods: This retrospective study examined consecutive patients who underwent colonoscopy for acute LGIB at a single tertiary hospital between November 2020 and May 2023.
Int J Legal Med
September 2025
University Center of Legal Medicine Lausanne-Geneva, University of Geneva, Geneva University Hospitals, Rue Michel-Servet 1, 1211, Geneva 4, Switzerland.
In the past 10 years, the Multi-phase Post-mortem Computed Tomography Angiography (MPMCTA) has considerably improved the quality and precision of postmortem diagnoses, particularly in cases with vascular implication. MPMCTA is known to have higher sensitivity for detecting the source of a hemorrhage than autopsy. Death by upper gastro-intestinal (GI) bleeding is not so uncommon in forensic practice.
View Article and Find Full Text PDFInt J Pharm Pract
September 2025
Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Suthep Road, Suthep, Mueang, Chiang Mai 50200, Thailand.
Objectives: Proton pump inhibitors (PPIs) are commonly used among these patients to prevent upper gastrointestinal bleeding (UGIB) in anticoagulated patients. However, their clinical benefits among patients receiving OACs with a history of UGIB remain inconclusive. This study aimed to summarize the clinical benefits of PPIs for the secondary prevention of recurrent UGIB among patients using OACs.
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