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Purpose: Utilizing a participatory approach, we sought to co-design a 12-week Green Activity Program (GAP) with Hispanic/Latino individuals living with memory challenges and their care partners, local outdoor professionals, and healthcare providers.
Methods: Participants were recruited via convenience and snowball sampling in the Bronx, New York with Hispanic/Latino persons living with memory challenges and care partners, outdoor activity professionals, and interdisciplinary healthcare providers/dementia experts. Co-design occurred iteratively with 5 focus groups and 4 individual interviews lasting 30-90 min and focused on program and research design. Sessions were recorded and transcribed. Utilizing directed content analysis data was coded using a priori codes program design and research design.
Results: 21 participants completed co-design activities: ( = 8 outdoor activity professionals, = 6 Hispanic/Latino persons living with memory challenges and care partners, and = 7 interdisciplinary healthcare providers/dementia experts). Participant preferences for program design were captured by subcodes (30-90 min), (4-8 sessions), and (in-person and phone). Participants' preferred nature activities included group exercise and outdoor crafts [crocheting], outcomes of social participation, connectedness to nature, decreased loneliness, and stewardship were identified. Preferred language for recruiting and describing the program were "memory challenges," "Hispanic/Latino," and "wellbeing." were identified including community-based organizations and primary care.
Conclusion: Co-design was a successful form of engagement for people living with memory challenges that enabled participants to help design key elements of the GAP and research design. Our processes, findings, and recommendations for tailoring co-design to engage Hispanic/Latino people living with memory challenges can inform the development of other programs for this population.
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http://dx.doi.org/10.3389/fnagi.2024.1401255 | DOI Listing |
CNS Drugs
September 2025
Global Health Neurology Lab, Sydney, NSW, 2150, Australia.
Acute ischemic stroke (AIS) remains a leading cause of mortality and long-term disability globally, with survivors at high risk of recurrent stroke, cardiovascular events, and post-stroke dementia. Statins, while widely used for their lipid-lowering effects, also possess pleiotropic properties, including anti-inflammatory, endothelial-stabilizing, and neuroprotective actions, which may offer added benefit in AIS management. This article synthesizes emerging evidence on statins' dual mechanisms of action and evaluates their role in reducing recurrence, improving survival, and mitigating cognitive decline.
View Article and Find Full Text PDFJ Appl Gerontol
September 2025
Division of Social Welfare, Kangnam University, Yongin-si, Korea.
Welfare technology is becoming essential for promoting older adults' well-being, reducing health risks, and enhancing social engagement. While many welfare technology living lab studies focus on single devices, integrating multiple digital tools may offer greater emotional and cognitive benefits. This study investigates the effects of a living lab-based intervention using two digital devices: one targeting cognitive function (D1) and the other targeting physical function (D2).
View Article and Find Full Text PDFFront Immunol
September 2025
Bacterial Scientific Area, GSK Vaccine, Siena, Italy.
Background: Protein-polysaccharide conjugate vaccines rely on the induction of T-cell-dependent responses that support germinal center (GC) reactions to potentiate the expansion of antigen-specific memory B-cell (MBC) populations and high-avidity antibody responses. The effects of adjuvants on B-cell and antibody responses are well described for protein antigens but remain largely unexplored for conjugated polysaccharidic antigens.
Methods: We assessed the effects of five adjuvants present in licensed vaccines (AS01, AS03, AS04, and aluminum hydroxide [Alum]) or under clinical evaluation (AS37) on the magnitude and quality of antigen-specific antibody responses and local/systemic B-cell responses.
Front Sports Act Living
August 2025
Department of Robotics, College of Science and Engineering, Ritsumeikan University, Kusatsu, Shiga, Japan.
Improvement of physical and cognitive capabilities through physical activity (PA) contributes to well-being in older age. Unfortunately, many older adults lack sufficient PA, due to reasons such as PA not being enjoyable for them. As a result, older adults are unable to maintain their motivation for the initiation and continuation of PA.
View Article and Find Full Text PDFCan J Pain
September 2025
School of Nursing, Midwifery, Allied and Public Health, Canterbury Christ Church University, Canterbury, UK.
Hemophilia is a bleeding disorder characterized by recurrent bleeding into muscles and joints. Many people with hemophilia experience multiple traumatic painful bleeding episodes, meaning that pain is often a significant problem for people with hemophilia, with a potentially high prevalence of posttraumatic stress and posttraumatic stress disorder symptoms. Current pain treatments are often ineffective and do not consider pain memories, which are experienced by almost half of people with posttraumatic stress disorder and which has not been explored in people with hemophilia.
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