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Article Abstract
The aging population and increasing incidence of trauma among younger age groups have heightened the increasing demand for reliable implant materials. Effective implant materials must demonstrate rapid osseointegration and strong antibacterial properties to ensure optimal patient outcomes and decrease the chance of implant rejection. This study aims to enhance the bone-implant interface by utilizing 45S5 bioglass modified with various concentrations of FeO as a coating material. The effect of the insertion of FeO into the bioglass structure was studied using Raman spectroscopy which shows that with the increase in FeO concentration, new vibration bands associated with Fe-related structural units appeared within the sample. The bioactivity of the prepared glasses was evaluated using immersion tests in simulated body fluid, revealing the formation of a calcium phosphate-rich layer within 24 h on the samples, indicating their potential for enhanced tissue integration. However, the sample modified with 8 mol% of FeO showed low reactivity, developing a calcium phosphate-rich layer within 96 h. All the bioglasses showed antibacterial activity against the and bacteria. The modified bioglass did not present significant antibacterial properties compared to the bioglass base.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11201570 | PMC |
| http://dx.doi.org/10.3390/biomimetics9060325 | DOI Listing |
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