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http://dx.doi.org/10.1080/15265161.2024.2362553 | DOI Listing |
Cell Biochem Biophys
September 2025
Medical Biotechnology Research Center, School of Paramedical Sciences, Guilan University of Medical Sciences, Rasht, Iran.
In cardiovascular research, melatonin has shown promise in exhibiting antifibrotic properties and modulating endoplasmic reticulum (ER) stress. However, the exact mechanism by which it influences myocardial fibrosis has not been fully clarified. Therefore, this research aimed to investigate the inhibitory effect of melatonin on the progression of myocardial fibrosis through a mechanism involving the BIP/PERK/CHOP signaling pathway, both in silico and in vivo experimental models.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
September 2025
Institute of Computer Science, Friedrich-Schiller-Universität, Fürstengraben 1, 07743, Jena, Thuringia, Germany.
Purpose: Cerebral aneurysms are blood-filled bulges that form at weak points in blood vessel walls, and their rupture can lead to life-threatening consequences. Given the high risk associated with these aneurysms, thorough examination and analysis are essential for determining appropriate treatment. While existing tools such as ANEULYSIS and its web-based counterpart WEBANEULYSIS provide interactive means for analyzing simulated aneurysm data, they lack support for collaborative analysis, which is crucial for enhancing interpretation and improving treatment decisions in medical team meetings.
View Article and Find Full Text PDFJ Behav Med
September 2025
Department of Psychology, University of Wisconsin-La Crosse, La Crosse, WI, USA.
Latent profile analysis (LPA) is in the finite mixture model analysis family and identifies subgroups by participants' responses to continuous variables (i.e., indicators); participants' probable membership in each subgroup is based on the similarity between the subgroup's prototypical responses and the person's unique responses.
View Article and Find Full Text PDFJ Behav Med
September 2025
Department of Psychology and Human Development, Vanderbilt University, 230 Appleton Place, Nashville, TN, 37203‑5721, USA.
Estimating statistical power is essential for designing behavioral medicine studies efficiently and conserving finite resources. Sometimes behavioral medicine researchers are interested in calculating power for 1-sided z-tests of individual parameters (e.g.
View Article and Find Full Text PDFApoptosis
September 2025
The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, 182 Chunhui Road, Longmatan District, Luzhou, 646000, China.
Diabetic cardiomyopathy (DCM) is a severe cardiovascular complication of diabetes mellitus, characterized by pathological changes such as cardiomyocyte hypertrophy, necrosis, and myocardial fibrosis, which can ultimately lead to heart failure. However, its underlying mechanisms remain incompletely understood, limiting the development of effective therapeutic approaches. In recent years, the critical roles of oxidative stress and ferroptosis in the pathogenesis of DCM have attracted increasing attention.
View Article and Find Full Text PDF