Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/jxb/erae230 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Many species undergo actin-based motility to promote cell-cell spread during infection. Rickettsial genomes encode two motility effectors, RickA and Sca2. In the spotted fever group species , RickA acts early in infection by activating the host Arp2/3 complex; Sca2 acts later by mimicking the structure and function of eukaryotic formins.
View Article and Find Full Text PDFBiochemical Changes in Prostate Cancer: FMNL1 and PAK1 in Plasma and Urine.
Curr Issues Mol Biol
August 2025
Department of Basic Oncology, Institute of Oncology, Istanbul University, 34093 Istanbul, Turkey.
Prostate cancer is a clinically heterogeneous disease. Since PSA is not cancer-specific, and due to the bone metastases seen in the advanced stage and bone deformations caused by hormone therapy, it is necessary to use new biomarkers. Formin-like-protein 1 (FMNL1), a member of the formin protein family, is of great importance in actin polymerization, cell attachment, and migration processes.
View Article and Find Full Text PDFThe actin module of endocytic internalization in Aspergillus nidulans: A critical role of the WISH/DIP/SPIN90 family protein Dip1.
PLoS Genet
August 2025
Department of Molecular and Cellular Biosciences, CSIC Centro de Investigaciones Biológicas Margarita Salas, Madrid, Spain.
Using fluorescent protein-tagged F-actin reporters we studied the actin cytoskeleton in Aspergillus nidulans. F-actin probes labeled endocytic patches, contractile actin rings and the Spitzenkörper (SPK), but not exocytic cables generated by the SPK-associated formin, illuminated only by tropomyosin. The SPK actin mesh contains tropomyosin and capping protein, but not fimbrin or Arp2/3, showing that it does not involve branched actin.
View Article and Find Full Text PDFRole of Gα-MAPK interaction in mating of .
Mol Biol Cell
August 2025
Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710.
Guidance of cell growth or movement in response to chemical cues in the environment is critical for many cell behaviors. Budding yeast orientation of polarized growth in response to gradients of mating pheromones provides a tractable model to address how cells accurately assess small spatial differences in chemical concentrations. Pheromones bind to receptors that act through heterotrimeric G proteins to promote activation of the MAPK Fus3.
View Article and Find Full Text PDFAligned Collagen Fibers Drive Distinct Traction Force Signatures to Regulate Contact Guidance.
ACS Nano
August 2025
Department of Chemical and Biological Engineering, Iowa State University, 2114 Sweeney Hall, Ames, Iowa 50011, United States.
Cellular forces on deposited nonfibrillar extracellular matrix (ECM) have been measured extensively. However, , cells exert traction forces on collagen fibers within the ECM. Oftentimes, collagen fibers are aligned, as seen in cancer, fibrosis, and during wound healing.
View Article and Find Full Text PDF