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A metal- and oxidant-free, radical C-H selenylative and tellurylative annulation of -(2-alkynyl)anilines with diorganyl dichalcogenides is developed under electrochemical conditions for the sustainable synthesis of valuable 3-selanyl/tellanylquinolines up to 92% yield at room temperature. The developed protocol required only electricity as the green reagent and offers high atom economy, broad substrate scope, and efficient scalability.
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http://dx.doi.org/10.1039/d4cc01780c | DOI Listing |
Chem Commun (Camb)
July 2024
Department of Chemistry, Birla Institute of Technology and Science, Pilani (BITS Pilani), Hyderabad Campus, Jawahar Nagar, Kapra Mandal, Hyderabad-500078, Telangana, India.
A metal- and oxidant-free, radical C-H selenylative and tellurylative annulation of -(2-alkynyl)anilines with diorganyl dichalcogenides is developed under electrochemical conditions for the sustainable synthesis of valuable 3-selanyl/tellanylquinolines up to 92% yield at room temperature. The developed protocol required only electricity as the green reagent and offers high atom economy, broad substrate scope, and efficient scalability.
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