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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165374PMC
http://dx.doi.org/10.1001/jamanetworkopen.2024.15917DOI Listing

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Assessing the Prognostic Accuracy of the PSS, pSOFA, and SIRS for In-Hospital Mortality in Children with Suspected Infection in Non-ICU Settings: A Multicenter Retrospective Study.

Int J Infect Dis

September 2025

Department of Clinical Laboratory, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health National Children's Regional Medical Center, Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, 311121, China. Electronic address: qingye

Objectives: To systematically compare the predictive accuracy of the Phoenix Sepsis Score (PSS), the Pediatric Sequential Organ Failure Assessment (pSOFA), and systemic inflammatory response syndrome (SIRS) in assessing in-hospital mortality risk among pediatric sepsis patients in non-ICU wards, thereby providing evidence-based support for clinical risk stratification.

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Early enteral nutrition in critically-ill patients.

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Department of Gastroenterology and Hepatology, Creighton University School of Medicine, Phoenix, AZ 85012, United States.

Critically ill patients have a variety of complex pathologies and are in a multifarious state of catabolism supplanted by external and internal factors. Early enteral nutrition (EEN) is defined as the initiation of enteral feeding within 24-48 hours of hospitalization. Previous studies show the benefits of EEN include supporting the healing process through preservation of the gut mucosa, modulation of the immune response, and suppression of inflammation.

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