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Emotionality and self-regulation are crucial for positive development, especially during early adolescence when youths experience normative increases in behavioral problems and declines in prosociality. Using Latent Profile Analysis (LPA-a person-oriented technique to identify patterns of functioning individuals), we identified youths' profiles based on dimensions of mother-reported negative emotionality (NE; anger/frustration, sadness/depressive mood), and Effortful Control (EC; attentional, activation and inhibitory control) and examined concurrent associations with self- and mother-reported aggressive and prosocial behaviors. We included a cross-national sample of 530 youths ( 11.43; 49% males) from Colombia (17%), Italy (36%), and United States (47%). We identified four profiles: Adjusted (38%; low NE; high EC)-lowest aggression, highest prosociality; Average (34%; average NE and EC)-average aggression and prosociality; Emotional-regulated (20%; high NE; average EC)-average aggression and high prosociality; and Emotional-dysregulated (8%; high NE; low EC)-highest aggression, low prosociality. We highlight associations of different emotion-regulation patterns with specific behavioral responses in early adolescence.
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http://dx.doi.org/10.1016/j.paid.2023.112298 | DOI Listing |
Ind Health
September 2025
Dokuz Eylul University, Faculty of Medicine, Department of Occupational Medicine, Turkey.
Jockeys endure considerable physical and psychological demands, rendering them vulnerable to occupational injuries such as fractures, concussions, and soft tissue damage. This descriptive case series presents the medical and occupational histories of three professional jockeys with long-term disabilities following work-related accidents. Each individual commenced their jockey career in early adolescence.
View Article and Find Full Text PDFNeurotoxicology
September 2025
Laboratory of Pharmacology of Inflammation and Behavioral (LAFICO), Health Science Institute, Federal University of Pará, Belém 66075110, PA, Brazil. Electronic address:
Ketamine has been widely used as a recreational substance by adolescents and young adults in nightclubs and raves in an acute manner, especially during the weekend. Considering the scarcity of evidence on the harmful consequences of adolescent ketamine recreational use on the central nervous system, primarily related to motor function, this study aimed to investigate the behavioral, biochemical, and neurochemical consequences on motor function induced by ketamine use, evaluating the motor cortex, cerebellum, and striatum in early abstinence. Adolescent female Wistar rats (28 days old) received ketamine by intranasal route (10mg/kg/day) for 3 consecutive days.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Faculty of Applied Sciences, Macao Polytechnic University, Macao. Electronic address:
Osteosarcoma (OS), the most prevalent primary bone malignancy in adolescents, is characterized by aggressive progression and early metastasis. However, the epigenetic drivers of its metastatic heterogeneity remain poorly understood. Herein, we integrated bulk DNA methylation profiling and single-cell RNA sequencing (scRNA-seq) to elucidate the epigenetic mechanisms driving OS metastatic heterogeneity.
View Article and Find Full Text PDFJ AAPOS
September 2025
Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Of 894,375 Israeli adolescents undergoing standardized medical and ocular assessments in our nationwide cross-sectional study, 2,622 (0.3%) had autism spectrum disorder (ASD). Adolescents with ASD had significantly higher adjusted odds of both myopia and astigmatism compared with peers who did not have ASD.
View Article and Find Full Text PDFProg Neuropsychopharmacol Biol Psychiatry
September 2025
Department of Women's and Children's Health, SciLifeLab, Uppsala University, Sweden. Electronic address:
Estrogens are suggested to affect mood by binding to widespread estrogen receptors in the brain and therewith modulating a variety of neurosignaling pathways. Single nucleotide polymorphisms (SNPs) in the genes encoding estrogen receptors might influence these actions and thereby play a role in the genetic foundation of mood disorders. Several SNPs in the estrogen receptor 1 (ESR1) gene have been studied in relation to anxiety and depression, while confounders and interaction with psychosocial factors have largely been overlooked.
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