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We examine run-and-tumble disks in two-dimensional systems where the particles also have a Magnus component to their dynamics. For increased activity, we find that the system forms a motility-induced phase-separated (MIPS) state with chiral edge flow around the clusters, where the direction of the current is correlated with the sign of the Magnus term. The stability of the MIPS state is non-monotonic as a function of increasing Magnus term amplitude, with the MIPS region first extending down to lower activities followed by a break up of MIPS at large Magnus amplitudes into a gel-like state. We examine the dynamics in the presence of quenched disorder and a uniform drive and find that the bulk flow exhibits a drive-dependent Hall angle. This is a result of the side jump effect produced by scattering from the pinning sites and is similar to the behavior found for skyrmions in chiral magnets with quenched disorder.
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http://dx.doi.org/10.1140/epje/s10189-024-00431-w | DOI Listing |
Sci Rep
August 2025
Department of Radiology, Molecular Imaging Program at Stanford (MIPS), Stanford University School of Medicine, Stanford, CA, USA.
Chimeric Antigen Receptor (CAR) T-cell therapy has demonstrated efficacy in children and young adult patients with acute lymphoblastic leukemia (ALL). The purpose of our study was to investigate thymus size changes after CAR T-cell therapy, explore the associated clinical conditions, and assess survival differences of patients who underwent CAR T-cell therapy, we conducted a single-center retrospective study of children and young adult patients who underwent CAR T-cell therapy for ALL between April 2015 and October 2023.We measured the volume of the thymus on pre- and post-CAR T-cell chest CT scans of 20 patients (median [IQR] age, 18[11] years; 11 females).
View Article and Find Full Text PDFACS Sens
August 2025
Sensor Engineering Department, Faculty of Science and Engineering, Maastricht University, 6200 MD Maastricht, The Netherlands.
Xylazine adulterated Fentanyl is considered one of the deadliest drug threats ever faced in the United States. However, due to the complexity of the illegal drug supply, xylazine detection in the frame of drug-checking (harm reduction) remains an unsolved challenge, one which has cost numerous lives across North America. In this work, we present two sensor platforms for detecting xylazine in drug-checking applications.
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August 2025
Department of Analytical Chemistry, Institute of Chemistry, São Paulo State University (UNESP), Araraquara, São Paulo 14801-970, Brazil.
Sulfathiazole (STZ) is an antibiotic used for bacterial infections in humans and to boost farm animal health. Overuse can lead to harmful antibiotic residues in meat, posing risks to human health. This also contributes to the rise of antibiotic-resistant bacteria.
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August 2025
Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, São Paulo 09210-580, Brazil.
Synthetic cannabinoids (SCs), a prominent class of new psychoactive substances, pose growing challenges to public health due to their severe toxic effects and widespread global presence. In this study, we employed computational methods to develop molecularly imprinted polymers (MIPs) for the selective recognition of seven SCs, chosen based on seizure reports from the Narcotics Examination Unit of the Scientific Police of the State of São Paulo. Density functional theory and extended tight binding for geometry, frequency, and noncovalent model 2 (GFN2-xTB) calculations were used to optimize the molecular geometries and predict ideal monomer-solvent combinations for MIP synthesis.
View Article and Find Full Text PDFBiosens Bioelectron
November 2025
State Key Laboratory of Chemical Safety, College of Control Science and Engineering, China University of Petroleum (East China), Qingdao, 266580, China. Electronic address:
Wearable biochemical sensors enabling non-invasive monitoring of biomarkers in bodily fluids play a pivotal role in advancing personalized healthcare. The state-of-the-art wireless and wearable biochemical sensors still suffer from large form factors, poor detection accuracy due to sample-to-sample variation, short and weak wireless communication, and difficulty to integrate with data processing algorithm on a system level. To solve these problems, this work develops an all-range wireless and wearable biochemical sensing platform which can be integrated in a diaper for monitoring four urine biomarkers (dimethylamine, creatinine, glucose, and H) with two switchable wireless modes.
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