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http://dx.doi.org/10.1016/j.cub.2024.05.035 | DOI Listing |
Plant Biol (Stuttg)
June 2025
Instituto de Biociências, Universidade Federal de Jataí, Jataí, Goiás, Brazil.
Gall-inducing organisms cause anatomical, micromorphometric, histochemical, and immunocytochemical modifications in the cell walls of host plant organs and tissues, leading to gall formation. Natural enemies, such as inquilines, interact with the gall by feeding on its tissues and modifying it structurally and chemically, as may occur in globoid leaf galls induced by Neolithus fasciatus on Sapium glandulosum. The inquiline maintains most primary and secondary metabolites in the protoplast of gall cells.
View Article and Find Full Text PDFmBio
April 2025
Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
is one of the leading causes of pulmonary infections caused by non-tuberculous mycobacteria. The ability of to establish a chronic infection in the lung relies on a series of adaptive mutations impacting, in part, global regulators and cell envelope biosynthetic enzymes. One of the genes under strong evolutionary pressure during host adaptation is , which participates in the elaboration of the arabinan domains of two major cell envelope polysaccharides: arabinogalactan (AG) and lipoarabinomannan (LAM).
View Article and Find Full Text PDFAppl Environ Microbiol
March 2025
Department of Food Science & Technology, University of California, Davis, California, USA.
Prebiotic oligosaccharides are dietary supplements that modulate the intestinal gut microbiome by selectively nourishing subsets of the microbial community with a goal to enhance host health. To date, the diversity of polysaccharide compositions in the fiber consumed by humans is not well represented by the limited scope of oligosaccharide compositions present in current commercial prebiotics. Recently, our UC Davis group developed a novel method to generate oligosaccharides from any polysaccharide fiber, termed enton's nitiation oward efined ligosaccharide roups (FITDOG).
View Article and Find Full Text PDFProc Natl Acad Sci U S A
April 2024
Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523-1682.
is increasingly recognized as the causative agent of chronic pulmonary infections in humans. One of the genes found to be under strong evolutionary pressure during adaptation of to the human lung is which encodes an arabinosyltransferase required for the biosynthesis of the cell envelope lipoglycan, lipoarabinomannan (LAM). To assess the impact of patient-derived mutations on the physiology and virulence of , mutations were introduced in the isogenic background of ATCC 19977 and the resulting strains probed for phenotypic changes in a variety of in vitro and host cell-based assays relevant to infection.
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