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Childhood vaccinations are among the most cost-effective health interventions. Yet, in India, where immunisation services are widely available free of charge, a substantial proportion of children remain unvaccinated. We revisit households 30 months after a randomised experiment of a health information intervention designed to educate mothers on the benefits of child vaccination in Uttar Pradesh, India. We find that the large short-term effects on the uptake of diphtheria-pertussis-tetanus and measles vaccination were sustained at 30 months, suggesting the intervention did not simply bring forward vaccinations. We apply causal forests and find that the intervention increased vaccination uptake, but that there was substantial variation in the magnitude of the estimated effects. We conclude that characterising those who benefited most and conversely those who benefited least provides policy-makers with insights on how the intervention worked, and how the targeting of households could be improved.
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http://dx.doi.org/10.1016/j.jhealeco.2024.102899 | DOI Listing |
J Drug Target
September 2025
Department of Pharmaceutics, ShriRam College of Pharmacy, Banmore, Morena-476444, Madhya Pradesh, India.
Tuberculosis (TB) continues to cause significant global mortality, highlighting the need for improved drug delivery systems. The objective of this paper focuses in describing the formulation, optimization and in vivo assessment of rifampicin encapsulated PLGA microparticles for site-specific inhalation therapy. Microparticles for inhalation were produced by spray drying, and the DoE methodology was applied to reach the most suitable aerodynamic properties (mass median aerodynamics diameter (MMAD) 2.
View Article and Find Full Text PDFInt J Pharm X
December 2025
Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University Uttar Pradesh, Sector-125, Noida 201313, India.
Intestinal inflammation particularly inflammatory bowel disease poses significant clinical challenges due to its chronic nature, limited treatment efficacy and adverse effects of conventional therapies like corticosteroids and biologics. Biomimetic nanocarriers have emerged as a transformative strategy to overcome these limitations by leveraging natural cell membranes for targeted drug delivery. This review critically examines the application of biomimetic nanocarriers as precision therapeutics for intestinal inflammation.
View Article and Find Full Text PDFJ Acute Med
September 2025
All India Institute of Medical Sciences (AIIMS) Department of Anaesthesiology and Critical Care Bhopal, Madhya Pradesh India.
In critically ill patients, there is complexity and dynamicity of the disease as well as absence of specific template to cover all aspects of the diagnosis. Improving accuracy in the diagnosis documentation is not only an important aspect in the communication among clinicians, other healthcare providers and administrators for better patient's clinical management; their financial aspects and quality metrics; but might also influence the future research depending on these documentations. This brief report highlights a systematic approach for updated daily as well as final diagnosis in critically ill patients.
View Article and Find Full Text PDFNepal J Epidemiol
September 2025
Sir Seewoosagur Ramgoolam Medical College, Belle Rive, Mauritius.
Background: Arthritis affects millions of people worldwide; however, its mismanagement remains a growing global challenge, resulting in reduced quality of life (QoL) and disability. Digital health (DH), including smartphones, could be the key to solving this problem. Specific evidence-based reviews on the use of DH in this context are lacking.
View Article and Find Full Text PDFIndian J Dermatol
September 2025
Department of Dermatology, Krishnanagar Institute of Medical Sciences, Krisnanahgar, Nadia, West Bengal, India E-mail: