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Purpose: Whether Internet of Things (IoT)-based home respiratory muscle training (RMT) benefits patients with comorbid chronic obstructive pulmonary disease (COPD) remains unclear. Therefore, this study aims to evaluate the effectiveness of IoT-based home RMT for patients with COPD.
Patients And Methods: Seventy-eight patients with stable COPD were randomly divided into two groups. The control group received routine health education, while the intervention group received IoT-based home RMT (30 inspiratory muscle training [IMT] and 30 expiratory muscle training [EMT] in different respiratory cycles twice daily for 12 consecutive weeks). Assessments took place pre-intervention and 12 weeks post-intervention, including lung function tests, respiratory muscle strength tests, the mMRC dyspnea scale, CAT questionnaires, the HAMA scale, and 6-month COPD-related readmission after intervention.
Results: Seventy-four patients with COPD were analyzed (intervention group = 38, control group = 36), and the mean age and FEV of the patients were 68.65 ± 7.40 years, 1.21 ± 0.54 L. Compared to those of the control population, the intervention group exhibited higher FEV/FVC (48.23 ± 10.97 vs 54.32 ± 10.31, = 0.016), MIP (41.72 ± 7.70 vs 47.82 ± 10.99, = 0.008), and MEP (42.94 ± 7.85 vs 50.29 ± 15.74, = 0.013); lower mMRC (2.00 [2.00-3.00] vs 1.50 [1.00-2.00], < 0.001), CAT (17.00 [12.00-21.75] vs 11.00 [9.00-13.25], < 0.001), and HAMA (7.00 [5.00-9.00] vs 2.00 [1.00-3.00], < 0.001) scores; and a lower incidence rate of 6-month readmission (22% vs 5%, = 0.033).
Conclusion: Compared with no intervention, IoT-based home RMT may be a more beneficial intervention for patients with COPD.
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http://dx.doi.org/10.2147/COPD.S454804 | DOI Listing |
J Eat Disord
September 2025
Center for Nutrition and Therapy (NuT), University of Applied Sciences Muenster, Corrensstraße 25, 48149, Muenster, Germany.
Eating disorders are primarily associated with women and an obsession with thinness. Recent research and social media content show that men are also concerned about their body image, striving for a muscular and athletic physique. To investigate eating disorder tendencies among male content creators with a mesomorphic body type (N = 26), a social media analysis was conducted on Instagram and TikTok over four weeks.
View Article and Find Full Text PDFSurg Endosc
September 2025
Department of Surgery and Cancer Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Introduction: This study aimed to evaluate surgeons' ergonomic satisfaction when using laparoscopic energy devices and to investigate how prolonged use affects muscle fatigue and surgical performance.
Methods: A two-part study, including a survey and a kinesiologic experiment, was conducted to compare 4 laparoscopic energy devices (D1-D4). Thirty surgeons completed a structured survey assessing ergonomic factors such as device weight, grip strength, handle design, comfort, and trigger location.
EMBO J
September 2025
School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, Australia.
Insulin resistance is a heritable risk factor for many chronic diseases; however, the genetic drivers remain elusive. In seeking these, we performed genetic mapping of insulin sensitivity in 670 chow-fed Diversity Outbred in Australia (DOz) mice and identified a genome-wide significant locus (QTL) on chromosome 8 encompassing 17 defensin genes. By taking a systems genetics approach, we identified alpha-defensin 26 (Defa26) as the causal gene in this region.
View Article and Find Full Text PDFGeroscience
September 2025
Research Institute of the McGill University Health Centre, 2155 Guy Street, Suite 500, Montreal, QC, H3H 2R9, Canada.
Frailty, often linked to sarcopenia, involves reduced muscle strength and mass. While sarcopenia has multiple causes, impaired muscle protein synthesis may contribute. Leucine and resistance training (RT) are anabolic stimuli, but the long-term effects of leucine combined with RT in pre/frail older women remain unclear.
View Article and Find Full Text PDFPflugers Arch
September 2025
Department of Science, University "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Hypoxia has been extensively studied as a stressor which pushes human bodily systems to responses and adaptations. Nevertheless, a few evidence exist onto constituent trains of motor unit action potential, despite recent advancements which allow to decompose surface electromyographic signals. This study aimed to investigate motor unit properties from noninvasive approaches during maximal isometric exercise in normobaric hypoxia.
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