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Article Abstract
Over 400 million years old, scorpions represent an ancient group of arachnids and one of the first animals to adapt to life on land. Presently, the lack of available genomes within scorpions hinders research on their evolution. This study leverages ultralong nanopore sequencing and Pore-C to generate the first chromosome-level assembly and annotation for the desert hairy scorpion, Hadrurus arizonensis. The assembled genome is 2.23 Gb in size with an N50 of 280 Mb. Pore-C scaffolding reoriented 99.6% of bases into nine chromosomes and BUSCO identified 998 (98.6%) complete arthropod single copy orthologs. Repetitive elements represent 54.69% of the assembled bases, including 872,874 (29.39%) LINE elements. A total of 18,996 protein-coding genes and 75,256 transcripts were predicted, and extracted protein sequences yielded a BUSCO score of 97.2%. This is the first genome assembled and annotated within the family Hadruridae, representing a crucial resource for closing gaps in genomic knowledge of scorpions, resolving arachnid phylogeny, and advancing studies in comparative and functional genomics.
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| http://dx.doi.org/10.1093/gbe/evae097 | DOI Listing |
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Unveiling the Genetic Blueprint of a Desert Scorpion: A Chromosome-level Genome of Hadrurus arizonensis Provides the First Reference for Parvorder Iurida.
Genome Biol Evol
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Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT, USA.
Article Synopsis
- Scorpions are an ancient group of arachnids, over 400 million years old, and one of the first land-dwelling animals, but research on their evolution is limited due to the lack of genomic data.
- This study used advanced sequencing techniques to create the first detailed chromosome-level genome assembly for the desert hairy scorpion, Hadrurus arizonensis, yielding a genome size of 2.23 Gb and reorganizing the data into nine chromosomes.
- The assembly identified a high number of protein-coding genes and complete arthropod orthologs, making it a valuable resource for understanding scorpion evolution, arachnid relationships, and for future genomic studies.
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