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Introduction: The purpose of this study was to determine if the time interval between two concussive events influences the number of days to asymptomatic status, days to return to play, or performance on common post-concussion assessments following the second concussion.
Methods: Data from 448 collegiate athletes and service academy cadets with two concussions (time between concussions: median 295.0 days [interquartile range: 125.0-438.2]), 40.0% female) were analyzed from Concussion Assessment Research and Education (CARE) Consortium institutions between 2014 and 2020. Days between concussions was the primary predictor variable. Primary outcome measures included time to asymptomatic and time to return to play following the second concussion. Secondary outcome measures included total number of symptoms, total symptom severity, Balance Error Scoring System total score, and Standardized Assessment of Concussion total score within 48 h of their second concussion.
Results: Time between concussions did not significantly contribute to the multivariate time to asymptomatic (p = 0.390), time to return to play (p = 0.859), or the secondary outcomes (p-range = 0.165-0.477) models. Time to asymptomatic (p = 0.619) or return to play (p = 0.524) did not differ between same-season and different-season concussions. Sex significantly contributed to the return to play (p = 0.005) multivariate model. Delayed symptom onset and immediate removal from play/competition significantly contributed to the total number of symptoms (p = 0.001, p = 0.014) and symptom severity (p = 0.011, p = 0.022) multivariate models.
Conclusion: These results suggest that in a population with a large period between injuries, the time between concussions may not be relevant to clinical recovery.
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http://dx.doi.org/10.1007/s40279-024-02015-2 | DOI Listing |
JAMA Netw Open
September 2025
Centre de recherche intégrée pour un système apprenant en santé et services sociaux, Centre intégré de santé et de services sociaux de Chaudière-Appalaches, Lévis, Québec, Canada.
Importance: Caregivers of community-dwelling older adults play a protective role in emergency department (ED) care transitions. When the demands of caregiving result in caregiver burden, ED returns can ensue.
Objective: To develop models describing whether caregiver burden is associated with ED revisits and hospital admissions up to 30 days after discharge from an initial ED visit.
Res Sports Med
September 2025
Çine State Hospital, Orthopedics and Traumatology Clinic, Aydın, Türkiye.
We wish to comment on the recent case report by Quintana-Cepedal et al. which highlights successful conservative management of a complete adductor longus rupture in a football player. In our retrospective cohort of 111 athletes with MRI-confirmed adductor lesions, we similarly observed high return-to-sport rates following structured exercise therapy, comparable to injection-based interventions.
View Article and Find Full Text PDFMol Ecol
September 2025
Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Many ant species show dramatic shifts in behaviour when infected with parasites, but the molecular basis of these behavioural changes is not well understood. An example is the wood ant, Formica aserva, which serves as an intermediate host for the lancet liver fluke, Dicrocoelium dendriticum. Infected ants leave their nests during the cool hours of the day, ascend a flower and then attach themselves to a petal with their mandibles.
View Article and Find Full Text PDFBrief Bioinform
August 2025
School of Information and Artificial Intelligence, Anhui Agricultural University, 130 Changjiang Road, Shushan District, Hefei, Anhui 230036, China.
Protein-nucleic acid binding sites play a crucial role in biological processes such as gene expression, signal transduction, replication, and transcription. In recent years, with the development of artificial intelligence, protein language models, graph neural networks, and transformer architectures have been adopted to develop both structure-based and sequence-based predictive models. Structure-based methods benefit from the spatial relationship between residues and have shown promising performance.
View Article and Find Full Text PDFPurpose: The global rise in popularity of basketball has prompted an increased emphasis on understanding the injury patterns affecting players. This study analysed injury epidemiology and return to sport outcomes in Division I male and female collegiate basketball players. The authors hypothesise that ankle injuries are amongst the most common in this population and that there are similarly comparable injury rates between genders.
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