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This retrospective study assessed the effectiveness and impact of implementing a Modified Early Warning System (MEWS) and Rapid Response Team (RRT) for inpatients admitted to the general ward (GW) of a medical center. This study included all inpatients who stayed in GWs from Jan. 2017 to Feb. 2022. We divided inpatients into GW and GW groups according to MEWS and RRT implementation in Aug. 2019. The primary outcome, unexpected deterioration, was defined by unplanned admission to intensive care units. We defined the detection performance and effectiveness of MEWS according to if a warning occurred within 24 h before the unplanned ICU admission. There were 129,039 inpatients included in this study, comprising 58,106 GW and 71,023 GW. The numbers of inpatients who underwent an unplanned ICU admission in GW and GW were 488 (.84%) and 468 (.66%), respectively, indicating that the implementation significantly reduced unexpected deterioration (p < .0001). Besides, 1,551,525 times MEWS assessments were executed for the GW. The sensitivity, specificity, positive predicted value, and negative predicted value of the MEWS were 29.9%, 98.7%, 7.09%, and 99.76%, respectively. A total of 1,568 warning signs accurately occurred within the 24 h before an unplanned ICU admission. Among them, 428 (27.3%) met the criteria for automatically calling RRT, and 1,140 signs necessitated the nursing staff to decide if they needed to call RRT. Implementing MEWS and RRT increases nursing staff's monitoring and interventions and reduces unplanned ICU admissions.
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http://dx.doi.org/10.1007/s10916-024-02046-2 | DOI Listing |
Front Immunol
September 2025
Department of Thoracic Surgery, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Background: While neoadjuvant chemoimmunotherapy shows promise for locally advanced esophageal squamous cell carcinoma (ESCC), optimal regimen selection remains challenging. This study compares perioperative outcomes between camrelizumab- and tislelizumab-based neoadjuvant chemoimmunotherapy in ESCC.
Methods: We conducted a retrospective analysis of 209 clinical stage II-IVA ESCC patients treated at Hebei Medical University Fourth Hospital (October 2020-December 2023) who underwent neoadjuvant chemoimmunotherapy (camrelizumab, n=119; tislelizumab, n=90) followed by esophagectomy.
J Gastrointest Surg
August 2025
Department of General Surgery, Tel Aviv Sourasky Medical Center, The Gray Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Background: Gastrectomy is central to the curative treatment of gastric cancer but carries substantial postoperative risks. Early reoperations represent severe complications, yet their impact on long-term oncologic outcomes remains unclear. Understanding this relationship is crucial for optimizing cancer care and patient counseling.
View Article and Find Full Text PDFAm J Hypertens
September 2025
Faculty of Pharmacy, Siam University, 38 Phet Kasem Road, Band Wa, Bangkok, 10160, Thailand.
Background: There has been incongruent evidence on the outcomes relating to whether continuing or withholding renin-angiotensin-aldosterone system inhibitors (RAASi) preoperatively. This study aimed to systematically analyse the effect of preoperative RAASi on perioperative and postoperative outcomes in patients undergoing non-cardiac surgeries.
Method: PubMed, Scopus, ScienceDirect, and Cochrane databases were used with no limitation of the starting date, till 30th September 2024.
Otolaryngol Head Neck Surg
September 2025
Otolaryngology-Head and Neck Surgery, College of Medicine, Hershey, Pennsylvania, USA.
Objective: Decannulation is a critical milestone in functional recovery after tracheostomy, but standardized guidelines are lacking. This study examined factors associated with tracheostomy decannulation success, comparing hospital utilization, adverse events, and survival outcomes between decannulated and non-decannulated patients.
Study Design: Retrospective, observational study.
World J Crit Care Med
September 2025
Department of Anaesthesiology, Tata Main Hospital, Jamshedpur 831001, India.
Unplanned intensive care unit (ICU) admissions (UP-ICU) following initial general ward placement are associated with poor patient outcomes and represent a key quality indicator for healthcare facilities. Healthcare facilities have employed numerous predictive models, such as physiological scores (, Acute Physiology and Chronic Health Evaluation II, Revised Trauma Score, and Mortality Probability Model II at 24 hours) and anatomical scores (Injury Severity Score and New Injury Severity Score), to identify high-risk patients. Although physiological scores frequently surpass anatomical scores in predicting mortality, their specificity for trauma patients is limited, and their clinical applicability may be limited.
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