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Objective: Elective-emergency admission control referred to allocating available inpatient bed capacity between elective and emergency hospitalization demand. Existing approaches for admission control often excluded several complex factors when making decisions, such as uncertain bed capacity and unknown true probability distributions of patient arrivals and departures. We aimed to create a data-driven newsvendor framework to study the elective-emergency admission control problem to achieve bed operational efficiency and effectiveness.
Methods: We developed a data-driven approach that utilized the newsvendor framework to formulate the admission control problem. We also created approximation algorithms to generate a pool of candidate admission control solutions. Past observations and relevant emergency demand and bed capacity features were modeled in a newsvendor framework. Using approximation algorithmic approaches (sample average approximation, separated estimation and optimization, linear programing-LP, and distribution-free model) allowed us to derive computationally efficient data-driven solutions with tight bounds on the expected in-sample and out-of-sample cost guaranteed.
Results: Tight generalization bounds on the expected out-of-sample cost of the feature-based model were derived with respect to the LP and quadratic programing (QP) algorithms, respectively. Results showed that the optimal feature-based model outperformed the optimal observation-based model with respect to the expected cost. In a setting where the unit overscheduled cost was higher than the unit under-scheduled cost, scheduling fewer elective patients would replace the benefit of incorporating related features in the model. The tighter the available bed capacity for elective patients, the bigger the difference of the schedule cost between the feature-based model and the observation-based model.
Conclusions: The study provides a reference for the theoretical study on bed capacity allocation between elective and emergency patients under the condition of the unknown true probability distribution of bed capacity and emergency demand, and it also proves that the approximate optimal policy has good performance.
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http://dx.doi.org/10.1111/jebm.12599 | DOI Listing |
Cureus
September 2025
Neurosurgery, Queen Elizabeth University Hospital, Glasgow, GBR.
Background Emergency neurosurgical referrals are a leading driver of on-call workload and unplanned admissions. Tracking their volume and case-mix supports safe staffing, imaging capacity, and bed planning across regional networks. The study included all emergency referrals made to the department between 2020 and 2022.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Department of Chemical Engineering and Materials Science, Yuan Ze University, Zhongli District, Taoyuan City 320315, Taiwan. Electronic address:
A systematic purification process for His-tagged enhanced green fluorescent protein (His-EGFP) from recombinant E. coli was developed using immobilized metal affinity chromatography (IMAC) in a packed bed format. Large-scale fermentation was conducted in a 5 L bioreactor, followed by cell harvesting and sonication-based disruption at 20 kHz and 4 °C.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Department of Pediatric Dentistry (Department of Preventive Dentistry), School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, No.44-1 Wenhua Road West, 250012 Jinan, Shandong, China.
Guided bone regeneration (GBR) is a prominent focus in biomedical materials research, yet few studies address practical clinical needs. GBR membranes must fulfill the "PASS" principles to be effective in surgery, but existing membranes often fall short in balancing antibacterial activity, controlled degradation, osteoinductive potential, and mechanical support. In this study, we employed laser powder bed fusion (LPBF) to fabricate a porous WE43 magnesium alloy scaffold suitable for large alveolar bone defects.
View Article and Find Full Text PDFBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
September 2025
Klinik für Palliativmedizin, Universitätsmedizin Göttingen (UMG), Georg-August-Universität Göttingen, Von-Siebold-Straße 3, 37075, Göttingen, Deutschland.
Introduction: Demographic change and rising patient numbers pose challenges for local access to palliative care units. Availability and accessibility as dimensions of spatial access, which have mostly been considered separately in previous studies, are integrated using the method "Enhanced Two-Step Floating Catchment Area" (E2SFCA) in order to identify regional differences by providing a more realistic picture of the care situation.
Methods: At the community level, an access index (Z) was calculated using the E2SFCA method.
J Acad Consult Liaison Psychiatry
September 2025
Department of Emergency Medicine, Oregon Health and Science University, Oregon, Portland, OR.
Introduction: Emergency department (ED) patients requiring inpatient psychiatric admission experience prolonged boarding times due to a nationwide deficit in inpatient bed capacity. These extended boarding times, which can last hours to days, introduce additional risks of harm, including missed home medications and omissions in care essential to chronic disease management. The overall aim is to reduce missed care components in ED patients with psychiatric illness awaiting inpatient psychiatry admission by using our novel checklist and mnemonic, SHEDS (sugar control, home medications, expiration time, documentation, social work, and psychiatry consults), coupled with an educational campaign.
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