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Ground target detection and positioning systems based on lightweight unmanned aerial vehicles (UAVs) are increasing in value for aerial reconnaissance and surveillance. However, the current method for estimating the target's position is limited by the field of view angle, rendering it challenging to fulfill the demands of a real-time omnidirectional reconnaissance operation. To address this issue, we propose an Omnidirectional Optimal Real-Time Ground Target Position Estimation System (Omni-OTPE) that utilizes a fisheye camera and LiDAR sensors. The object of interest is first identified in the fisheye image, and then, the image-based target position is obtained by solving using the fisheye projection model and the target center extraction algorithm based on the detected edge information. Next, the LiDAR's real-time point cloud data are filtered based on position-direction constraints using the image-based target position information. This step allows for the determination of point cloud clusters that are relevant to the characterization of the target's position information. Finally, the target positions obtained from the two methods are fused using an optimal Kalman fuser to obtain the optimal target position information. In order to evaluate the positioning accuracy, we designed a hardware and software setup, mounted on a lightweight UAV, and tested it in a real scenario. The experimental results validate that our method exhibits significant advantages over traditional methods and achieves a real-time high-performance ground target position estimation function.
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http://dx.doi.org/10.3390/s24051709 | DOI Listing |
Eur J Med Res
September 2025
Department of Zoology, Faculty of Science, Ain Shams University, Abbassia, Cairo, 11566, Egypt.
Nuclear receptors (NRs) are a superfamily of ligand-activated transcription factors that regulate gene expression in response to metabolic, hormonal, and environmental signals. These receptors play a critical role in metabolic homeostasis, inflammation, immune function, and disease pathogenesis, positioning them as key therapeutic targets. This review explores the mechanistic roles of NRs such as PPARs, FXR, LXR, and thyroid hormone receptors (THRs) in regulating lipid and glucose metabolism, energy expenditure, cardiovascular health, and neurodegeneration.
View Article and Find Full Text PDFHandb Exp Pharmacol
September 2025
National Institute of Biological Sciences, Beijing, China.
G protein-coupled receptors (GPCRs) engage multiple transducers to regulate distinct physiological processes. These transducers include various G proteins subtypes, GPCR kinases (GRKs), and β-arrestins. In addition to promoting receptor desensitization, β-arrestins serve as scaffolds for signaling via non-G protein pathways.
View Article and Find Full Text PDFBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
September 2025
Abteilung für Epidemiologie und Gesundheitsmonitoring, Robert Koch-Institut, Nordufer 20, 13353, Berlin, Deutschland.
Background: The prevalence of mental disorders in Germany is associated with socioeconomic position. International studies further indicate area-level correlations linking higher levels of socioeconomic deprivation with increased mental health burdens. However, these area-level associations have not yet been systematically examined in Germany and it is unclear whether socioeconomic disparities in mental health outcomes are contingent upon area-level socioeconomic deprivation.
View Article and Find Full Text PDFAerosp Med Hum Perform
September 2025
Introduction: Military fast jet pilots face significant physical challenges, including high Gz accelerations during dynamic maneuvers. The objectives of this study were threefold: 1) to record pilot movements during real flights, 2) to quantify head and trunk movements under standardized Gz conditions and during basic fighter maneuvers (BFMs), and 3) to categorize compensatory strategies used to mitigate physical strain.
Methods: A total of 20 Eurofighter pilots (mean age: 28.
One in five adolescents (10-19) live in sub-Saharan Africa. Despite the availability of policies targeted at this age group, policy formulation, implementation, and gains in adolescent health continue to be underwhelming. Actors or stakeholders are architects of policy, bringing their ideological values, interests, power, and positions to policy formulation and implementation and thus influencing the policy process.
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