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Background: Ulcerative colitis (UC) causes long-lasting inflammation and ulcers in the gut. Limited observational data are available linking dietary magnesium intake and UC. In the present study, we aimed to investigate the association between dietary magnesium intake and UC in adults.
Methods: The current population-based case-control study was performed on 109 UC patients and 218 age (±2 years) and sex-matched controls. The diagnosis of UC was made according to the standard criteria by a gastroenterology specialist. Dietary intakes were assessed using a validated self-administrated 106-item dish-based Food Frequency Questionnaire (FFQ). We also used a pretested questionnaire to collect data on potential confounders.
Results: Individuals in the top tertile of magnesium intake were less likely to have UC compared with those in the bottom tertile. A significant inverse relationship was found between dietary magnesium intake and UC (odds ratio [OR]: 0.32, 95% confidence interval [CI]: 0.18-0.59) in the crude model. This relationship was also observed when we took several potential confounding into account (OR: 0.30, 95% CI: 0.14-0.68).
Conclusions: Adherence to a magnesium-rich diet may have a role in preventing UC. However, further studies are needed to confirm our findings.
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http://dx.doi.org/10.1093/crocol/otae009 | DOI Listing |
J Hum Nutr Diet
October 2025
Haszard Biostatistics, Otago, New Zealand.
Introduction: Dependent older adults in residential aged care are at increased risk of inadequate micronutrient intakes. Knowledge of dietary intakes in this group is needed to inform clinical decision making and guide nutrition policy and menu planning. This study aimed to determine the usual intake and food sources of micronutrients of New Zealand aged-care residents.
View Article and Find Full Text PDFFood Nutr Res
August 2025
Centre for Nutrition, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Background: Sub-Saharan Africa is facing a dietary transition with both undernutrition and rising rates of non-communicable diseases. Adopting the reference diet proposed by the EAT-Lancet Commission can reduce both the environmental burden and improve health outcomes. However, whether this diet provides micronutrient adequacy in older adults in low-income settings has not been investigated.
View Article and Find Full Text PDFNat Sci Sleep
August 2025
Institute of Food and One Health, Leibniz University Hannover, Hanover, Lower Saxony, Germany.
Purpose: To assess the effects of magnesium bisglycinate supplementation on insomnia symptoms in healthy adults reporting poor sleep quality.
Patients And Methods: This randomized, double-blind, placebo-controlled trial enrolled 155 adults aged 18-65 years with self-reported poor sleep quality. Participants were randomly assigned to either magnesium bisglycinate supplementation (250 mg elemental magnesium, daily) or placebo capsules.
Chronobiol Int
September 2025
Faculty of Medicine & Health, School of Health Sciences, The University of Sydney, Sydney, Australia.
This study examines how dietary nutrient patterns vary among individuals with different chronotypes. In other words, this research explores the potential connections between nutrient intake and circadian rhythm. In this secondary data analysis, we used data from 3,072 adult participants (mean age: 30.
View Article and Find Full Text PDFBMC Endocr Disord
September 2025
Maternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.
Background: Gestational diabetes mellitus (GDM) is a common pregnancy complication closely associated with increased oxidative stress. The Oxidative Balance Score (OBS) integrates dietary and lifestyle factors influencing oxidative stress, yet its relationship with GDM remains unclear.
Methods: In this case-control study, 150 pregnant women with GDM and 170 healthy controls were recruited from primary healthcare centers in Urmia, Iran.