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http://dx.doi.org/10.1289/EHP14610 | DOI Listing |
Pediatr Blood Cancer
September 2025
Child Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Purpose: Children with B-acute lymphoblastic leukemia (B-ALL) treated in resource-intensive settings have a high likelihood of cure, but therapy is long, burdensome, and associated with substantial toxicities. Understanding parents' perceptions of the most disruptive and difficult aspects of B-ALL treatment is critical to future improvements in care. We aimed to understand which child side effects, chemotherapeutic agents, and aspects of leukemia care are rated difficult or disruptive by parents, and variations based on parent or child characteristics.
View Article and Find Full Text PDFJ Surg Educ
September 2025
Department of Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts. Electronic address:
Introduction: Senior residents near the end of their training must be prepared to start an independent practice. To become board-certified they must pass an oral exam, the ABS Certifying Exam (ABSCE). Prior work has introduced the resident Individual Clinical Evaluations (rICE), a low-cost tool developed to assess residents' clinical judgment in level-appropriate clinical scenarios.
View Article and Find Full Text PDFPrenat Diagn
September 2025
Program in Genetic Counseling, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Objective: This study aimed to explore participant reflections after receipt of prenatal genome sequencing (GS) results in the absence of fetal anomalies.
Methods: Participants invited to complete a semi-structured interview consented to future research, were English speaking, and were between 30 days and 1 year since the conclusion of their sequenced pregnancy. A total of 18 interviews were conducted with 21 participants (3 couples interviewed concurrently) representing 15 unique pregnancies (81% term deliveries, 14% terminated pregnancies, and 5% preterm delivery).
Hernia
September 2025
Cardiff University, Cardiff, UK.
Purpose: Mesh-augmented abdominal wall closure (Mesh prophylaxis) reduces incisional hernia rates in high-risk patients. In spite of a large body of evidence supporting its efficacy and safety, use of mesh prophylaxis is low in the US and UK, possibly due to negative perceptions of surgical mesh. This study aimed to assess the acceptability of mesh to patients and determine factors that influence acceptability.
View Article and Find Full Text PDFBiopreserv Biobank
September 2025
German Biobank Node, Charité - Universitätsmedizin Berlin, Berlin, Germany.
The German Biobank Node (GBN) coordinates the national network of academic biobanks in Germany; the German Biobank Alliance (GBA). At the beginning of 2025, the GBA consisted of 42 biobanks. With an upcoming strategic reorientation, the GBN/GBA was interested in understanding the perspectives of their community to ensure that strategic decisions were aligned with their needs and interests.
View Article and Find Full Text PDF