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http://dx.doi.org/10.20344/amp.20267 | DOI Listing |
Psychiatry Clin Psychopharmacol
August 2025
Interventional Psychiatry Program, St. Michael's Hospital, Toronto, Canada.
Background: Posttraumatic stress disorder (PTSD) is a severe, often difficult-to-treat condition, highlighting the need for innovative therapies. Interventional treatments, including neuromodulation, rapid-acting pharmacotherapies such as intravenous ketamine (IV-KET) and esketamine (ESK), and emerging psychedelic-assisted psychotherapies, offer promising solutions. This systematic review evaluates the efficacy, safety, and future research priorities of these treatments for PTSD.
View Article and Find Full Text PDFEur Neuropsychopharmacol
August 2025
Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
The pharmacology of antipsychotic drugs (APDs) is exceedingly complex with many of them showing a broad receptor interaction spectrum. We aimed to provide a reference work on receptor binding affinity, to quantify the breadth of receptor interaction of APDs and to analyze implications on clinical efficacy and classification. Binding affinity data were obtained from an open-source database and normalized to allow for direct comparison of affinity profiles across compounds and quantification of the receptor interaction breadth at the level of (1) individual drugs and (2) defined receptor groups.
View Article and Find Full Text PDFReprod Biol Endocrinol
May 2025
Students' Scientific Group of Systematic Reviews, Jagiellonian University, Krakow, Poland.
Background: One in six people experience infertility, often leading couples to seek Assisted Reproductive Technology (ART), which can be emotionally taxing. Anxiety and depression are common among individuals undergoing ART, highlighting the need for integrated mental health support, especially for women who face heightened risk of psychiatric disorders during their reproductive years. Despite the importance of psychiatric care, there is limited knowledge regarding the use of psychiatric medications among individuals undergoing ART.
View Article and Find Full Text PDFInt Clin Psychopharmacol
March 2025
Department of Neuroscience, University Psychiatric Center, Catholic University of Leuven, Psychiatry Research Group, Leuven, Belgium.
This study evaluates the impact of neuroscience-based nomenclature (NbN) training on psychiatric residents in Flanders, Belgium. Addressing Zemach et al.'s findings on NbN's potential, we investigated its application in clinical practice.
View Article and Find Full Text PDFAsian J Psychiatr
January 2025
Department of Psychiatry, Sheba Medical Center, Tel-Hashomer, Israel; Sackler School of Medicine, Tel Aviv University, Israel. Electronic address:
Neuroscience-based Nomenclature (NbN) is a pharmacologically-driven classification of psychotropics, aiming to revise the current indication-based classification (antipsychotics, antidepressants, anxiolytics etc.). Whereas the number of psychotropics has risen dramatically over the years, the current nomenclature preserves a rather narrow categorization that overlooks the rich neurobiological knowledge accumulated to date.
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