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Tear down this wall: phosphorylation regulates the internal interfaces of postsynaptic condensates. | LitMetric

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Article Abstract

Can the fusion/fission of biomolecular condensates be regulated in cells? In a recent study, Wu et al. show that phosphorylation of a key scaffold protein that drives condensates in postsynaptic densities modulates the apparent miscibility of underlying components, thus enabling intracondensate demixing-to-mixing transitions.

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http://dx.doi.org/10.1016/j.tcb.2024.02.007DOI Listing

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