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Background: Psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA) are inflammatory diseases with shared genetic backgrounds and clinical comorbidities. Headache, a common global health issue, affects over 50% of adults and encompasses various types, including migraine, tension-type, and cluster headaches. Migraine, the most prevalent, recurrent, and disabling type, is often associated with other medical conditions such as depression, epilepsy, and psoriasis, but little is known about the relationship between autoimmune disease and the risk of migraine.
Methods: A cross-sectional study was conducted from July to November 2022, enrolling 286 participants, including 216 with PsA, 70 with axSpA, and 87 healthy controls.
Results: Headache prevalence was significantly higher in the PsA (39.81%) and axSpA (45.71%) patients compared to the healthy controls. The prevalence of migraine without aura was also significantly higher in both the PsA (18.52%) and axSpA (28.57%) groups compared to the healthy controls.
Conclusions: These findings underscore the high burden of headache and migraine in PsA and axSpA participants, highlighting the need for improved management and treatment strategies for these patients.
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http://dx.doi.org/10.3390/biomedicines12020371 | DOI Listing |
Headache
September 2025
Hartford HealthCare Headache Center, Ayer Neuroscience Institute, University of Connecticut, West Hartford, Connecticut, USA.
Objective: (1) To estimate the impact of migraine on work productivity among employees at a large healthcare system in the United States. (2) To assess the knowledge and perception of migraine among employees and to evaluate the number of employees interested in receiving migraine care to help plan a future workplace migraine education and management program.
Background: Despite advances in treatment, migraine is underdiagnosed and undertreated and remains a leading cause of disability in the world.
Lupus Sci Med
September 2025
Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Background: SLE has increased risk of invasive pneumococcal disease due to immune dysregulation and immunosuppression. European Alliance of Associations for Rheumatology recommendations suggest sequential vaccination with conjugate vaccine, followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23). However, data on immunogenicity of sequential vaccination in SLE are limited.
View Article and Find Full Text PDFJ Child Neurol
September 2025
Department of Epidemiology and Environmental Health, State University of New York at Buffalo, Buffalo, NY, USA.
Mass psychogenic illness (MPI), also known as mass sociogenic illness, is a functional neurologic symptom disorder affecting multiple people simultaneously. This study presents a pediatric MPI outbreak involving abrupt-onset tics in LeRoy, NY, during 2011-2012. The analysis provides diagnostic evidence and highlights challenges with diagnosing MPI.
View Article and Find Full Text PDFFront Pain Res (Lausanne)
August 2025
University Otolaryngology, Providence, RI, United States.
Background: Rhinosinusitis (RS) is a leading reason for antibiotic prescriptions but treatment satisfaction is low. Misdiagnosis may contribute to poor outcomes, as migraine-often underrecognized-can mimic RS symptoms, with studies showing overlap between RS and migraine diagnoses. Our aims were to explore the demographics and clinical features of facial pain or pressure (FPP), its relationship with migraine and RS, and distinguish symptoms between these overlapping conditions.
View Article and Find Full Text PDFGastro Hep Adv
June 2025
Department of Internal Medicine, Gastroenterology Section, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Background And Aims: Extraintestinal symptoms are well-documented in systemic, inflammation-predominant conditions. Less is understood about extragastrointestinal symptoms among individuals with eosinophilic esophagitis (EoE) and non-EoE eosinophilic gastrointestinal diseases (EGIDs). We aimed to describe the differences in the frequency of patient-reported joint or leg pain and headache for EoE and non-EoE EGIDs individuals.
View Article and Find Full Text PDF