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http://dx.doi.org/10.3324/haematol.2023.283610 | DOI Listing |
J Affect Disord
September 2025
Department of Public Health, Bartholins Allé 2, Aarhus University, 8000, Aarhus C, Denmark. Electronic address:
Purpose: To study the association between internalizing and externalizing symptoms and prosocial behavior at age 7 years and pubertal timing in boys and girls.
Methods: This cohort study included 11,090 children from the Puberty Cohort within the Danish National Birth Cohort (DNBC). Data on internalizing and externalizing symptoms and prosocial behavior was derived from a parent-reported Strengths and Difficulties Questionnaire (SDQ) at age 7 years, and categorized as normal (lowest 79th percent), at-risk (80th - 89th percent) or abnormal (≥90th percent).
Imaging Neurosci (Camb)
September 2025
Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, United States.
Adolescent neuroimaging studies of sex differences in the human brain predominantly examine average differences between males and females. This focus on mean differences without probing relative distributions and similarities may contribute to both conflation and overestimation of sex differences and sexual dimorphism in the developing human brain. We aimed to characterize the variance in brain macro- and micro-structure in early adolescence as it pertains to sex at birth using a large sample of 9-11-year-olds from the Adolescent Brain Cognitive Development (ABCD) Study (N = 7,723).
View Article and Find Full Text PDFPsychoneuroendocrinology
August 2025
Department of Psychology, Stanford University, Stanford, CA, USA.
Childhood exposure to pollution has been associated with elevated levels of depressive symptoms during adolescence. Epidemiological studies have related exposure to pollution to altered pubertal timing; however, the effects of pollution exposure on levels of pubertal hormones and their developmental trajectories (i.e.
View Article and Find Full Text PDFSubst Use Misuse
September 2025
Department of Health Studies and Applied Educational Psychology, Teachers College, Columbia University, New York, New York, USA.
: We investigated the links between pubertal timing and tempo and the onset of cannabis, alcohol, and tobacco use among middle schoolers in Appalachian communities. : School surveys were administered to middle school students of the 6th grade and continuing through the spring of the 8th grade ( = 2,587; 49.4% boys), beginning in the fall at six-month intervals.
View Article and Find Full Text PDFFront Pharmacol
August 2025
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China.
Polycystic ovary syndrome (PCOS) represents a prevalent endocrine disorder affecting reproductive-aged women worldwide, characterized by a variety of reproductive, metabolic, and psychological manifestations. This condition disrupts menstrual cycles and fertility, and significantly compromises quality of life, while increasing the risk of severe health consequences, including cardiovascular diseases and endometrial carcinoma. Although the precise etiology of PCOS remains elusive, genetic and environmental factors are thought to contribute to its pathogenesis.
View Article and Find Full Text PDF