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Background: Tunneled dialysis catheters (TDCs) are a temporary bridge until definitive arteriovenous (AV) access is established. Our objective was to evaluate the time to TDC removal in patients who underwent AV access creations with TDCs already in place.
Methods: A single-center analysis of all AV access creations in patients with TDCs was performed (2014-2020). Primary outcome was time to TDC removal after access creation.
Results: There were 364 AV access creations with TDCs in place. The average age was 58 years, 44% of patients were female, and 64% were Black. The median time to TDC removal was 113 days (range, 22-931 days) with 71.4% having a TDC >90 days after access creation. Patients with TDC >90 days were often older (60 vs. 54.7), had hypertension (98.1% vs. 93.3%), were diabetic (65.4% vs. 47.1%), and had longer average time to maturation (107.1 vs. 55.4 days, P < 0.001) and first access (114 vs. 59.4 days, P < 0.001). Multivariable analysis showed that older age was associated with prolonged TDC placement (odds ratio [OR] 1.03, 95% confidence interval [CI] 1.01-1.05, P = 0.005) and prosthetic graft use was associated with shorter TDC indwelling time (OR 0.09, 95% CI 0.04-0.23, P ≤ 0.001). Kaplan-Meier analysis showed that 87% of TDCs were removed at 1 year.
Conclusions: The majority of patients with TDCs who underwent AV access creation had prolonged TDC placement. Prosthetic graft use was associated with shorter catheter times. Close follow-up after access placement, improving maturation times, and access type selection should be considered to shortened TDC times.
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http://dx.doi.org/10.1016/j.avsg.2023.12.065 | DOI Listing |
Alcohol Clin Exp Res (Hoboken)
August 2025
The Mind Research Network a Division of Lovelace Biomedical Research Institute, Albuquerque, New Mexico, USA.
Background: Fetal alcohol spectrum disorder (FASD) is associated with widespread neurocognitive deficits, including impairments in executive function, attention, and inhibitory control. However, understanding of the neural mechanisms underlying these deficits in young children 6-8 years of age remains limited. This study investigated functional connectivity (FC) alterations in key brain networks related to inhibitory control and executive function in children with FASD compared to typically developing controls (TDC).
View Article and Find Full Text PDFSensors (Basel)
July 2025
Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China.
As the resolution and conversion speed of time-to-digital conversion (TDC) chips continue to improve, the bit error rate also increases, leading to a decrease in the linearity of TDC and seriously affecting measurement accuracy. This paper presents a high-linearity, low-power-consumption, and wide dynamic range TDC that was achieved based on the SMIC 180 nm BCD process. Compared with previous research methods, the proposed phase arbiter structure can eliminate sampling errors and improve the linearity of TDC.
View Article and Find Full Text PDFOpt Express
February 2025
We propose and demonstrate a high-speed, high-sensitivity photon communication system based on a 16-pixel superconducting nanowire single-photon detector (SNSPD) array. This system integrates high-speed transmission of narrow optical pulses and multi-channel array high-speed signal detection and reception. By incorporating the proposed channel log-likelihood ratio correction and high-speed slot synchronization algorithm, the system's performance is enhanced.
View Article and Find Full Text PDFTo address the inherent trade-off between measurement range and precision as well as the limitations posed by ambiguity range in large-scale high-precision distance measurements, in this paper, we propose a dual femtosecond laser time-of-flight (ToF) sensor based on equivalent time-stretching and an FPGA-enabled coarse-fine fusion architecture. By employing a nonlinear asynchronous optical sampling (ACSOPS) strategy and cross-correlation peak extraction, femtosecond pulses delay is mapped from the femtosecond domain to the microsecond electronic domain, achieving a time-stretch ratio exceeding 10. The proposed system integrates dual-comb nonlinear ACSOPS with traditional pulse ToF measurement, reducing data redundancy, alleviating timing jitter-induced errors and enabling sub - micron ranging precision with low - bandwidth detectors A time-to-digital converter (TDC) core is implemented on the programmable logic (PL) side to perform millisecond-level coarse measurements over kilometer range.
View Article and Find Full Text PDFFront Immunol
August 2025
Department of Dermatology, State Key Laboratory of Complex Severe and Rare Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Objective: To evaluate the efficacy and safety of low-dose rituximab (RTX) in the treatment of pemphigus.
Methods: A systematic literature search was conducted across PubMed, Embase, the Cochrane Library, and ClinicalTrials.gov to identify eligible studies.