Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110674 | PMC |
| http://dx.doi.org/10.1016/j.chest.2024.02.006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Alveolar deadspace and intrapulmonary shunt in healthy individuals and in individuals who have recovered from COVID-19 infection.
Exp Physiol
September 2025
Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, UK.
Following acute COVID-19 infection, unvaccinated patients have been reported to exhibit elevated alveolar deadspace (̇V/̇V) and intrapulmonary shunt (̇Q/̇Q) fractions. However, as there is uncertainty surrounding the upper limits of normal for ̇V/̇V and ̇Q/̇Q, we sought to replicate the findings from a separate, previously reported cohort of COVID-19 patients that also included a healthy control group never infected with COVID-19. Data from 81 participants, classified into four different groups based on the severity of prior COVID-19 infection, were used.
View Article and Find Full Text PDFComputed cardiopulmonography: Effects of physical characteristics on lung parameter estimates.
Exp Physiol
July 2025
Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, UK.
Computed cardiopulmonography (CCP) is a technique that measures lung volumes (functional residual capacity and deadspace) together with novel parameters reflecting lung inhomogeneities (non-uniformities in lung inflation and deadspace path length). First, highly precise measurements of gas exchange are made during a nitrogen washout with a purpose-built molecular flow sensor. Second, an individual's lung physiology is then described by personalising the parameters of a bespoke cardio-respiratory model obtained by fitting the model to the data.
View Article and Find Full Text PDFThe search for the ultra-elusive: Can computed cardiopulmonography enhance early detection of gas exchange abnormality?
Exp Physiol
June 2025
Department of Kinesiology and Applied Health, University of Winnipeg, Winnipeg, Manitoba, Canada.
Effects of biologic therapy on novel indices of lung inhomogeneity in patients with severe type-2 high asthma.
BMJ Open Respir Res
February 2025
Nuffield Department of Medicine, University of Oxford, Oxford, UK
Introduction/aim: Lung inhomogeneity measures obtained using computed cardiopulmonography (CCP) are sensitive to small-airways disease. Here, we assessed changes in lung inhomogeneity in patients with type-2 high asthma treated with biological therapy and explored the relationship between inhomogeneity measures and conventional asthma disease markers.
Methods: This was an observational study of 91 severe type-2 high asthma patients recruited from a tertiary asthma clinic, of whom 67 subsequently started anti-IL5 or anti-IL5R biologics.
Computed Cardiopulmonography for the Detection of Early Smoking-Related Changes in the Lungs of Young Individuals Who Smoke.
Chest
May 2024
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, England; Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, England. Electronic address: