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Introduction: The smiley face rod method is an effective treatment for symptomatic terminal-stage spondylolysis. However, the risk factors for treatment failure are unknown. We investigated the association of pars defect type with the treatment outcomes of this method.
Methods: We retrospectively examined data from 34 patients (18.0±6.7 years) with terminal-stage spondylolysis who underwent surgery using the smiley face rod method. The mean follow-up period was 44.9±21.4 months. The patients were divided into 2 groups: pars defect without bone atrophy or sclerosis (group A; 18 patients), and with bone atrophy and sclerosis (group B; 16 patients). We evaluated and compared the visual analog scale (VAS) score for back pain, bone union rate, and time to return to preinjury athletics level between the groups. Fisher exact and paired tests were used to compare the variables between groups. The VAS score between the groups was compared using a 2-factor repeated-measures analysis of variance.
Results: Within groups, the VAS score was significantly different over time (<0.001). The VAS scores between groups were not significantly different. Patients in group A had a significantly higher bone union rate per pars at 6 months (group A, 65.7%; and group B, 37.5%, =0.028) and 24 months after surgery (group A, 97.1%; and group B, 75.0%, =0.011). All patients returned to their respective sports, and no significant differences were observed in the time to return to preinjury athletics level between the groups (=0.055).
Conclusions: The type of pars defect are associated with bone union after the smiley face rod method, but have little effect on postoperative symptoms.
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http://dx.doi.org/10.22603/ssrr.2023-0084 | DOI Listing |
J Gen Virol
September 2025
Department of Microbiology & Immunology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been linked to several neurological symptoms in coronavirus disease 2019 (COVID-19) patients; however, the molecular mechanisms underlying virus-induced neuroinflammation are not well identified. For example, the effect of SARS-CoV-2 infection of the substantia nigra pars compacta (SNpc) of the midbrain has not been addressed, in spite of its importance in dopaminergic signalling and neurodegenerative abnormalities. The purpose of this study was to understand the SARS-CoV-2-induced inflammatory response in the SNpc region of the brain.
View Article and Find Full Text PDFPain Med Case Rep
August 2025
Section of Physical Medicine and Rehabilitation, Department of Clinical Neurosciences, University of Calgary, Cumming School of Medicine, Calgary, AB, Canada.
Background: Low back pain is a prevalent issue with various etiologies, one of which includes pars interarticularis (pars) defects. While traditional fluoroscopic guidance has been the standard for administering injections, both fluoroscopic and ultrasound-guided injections for the management of low back pain have been shown to be similar in efficacy. The benefits of ultrasound guidance include real-time visualization, reduced radiation exposure, and improved patient access.
View Article and Find Full Text PDFNeurosci Res
August 2025
Department of Neurology, Hirosaki University Graduate School of Medicine, Japan.
We aimed to elucidate morphological changes in striatonigral projection neurons in a rat model of levodopa-induced dyskinesia (LID). Male Wistar rats underwent unilateral 6-hydroxydopamine lesioning to establish a hemiparkinsonian model. At 8 weeks postoperatively, the rats were allocated to either the levodopa-treated group or the saline-treated control group.
View Article and Find Full Text PDFLife (Basel)
July 2025
Department of Ophthalmology, Sestre milosrdnice University Hospital Center, Vinogradska cesta 29, 10000 Zagreb, Croatia.
We report a case of herpes simplex virus type 1 (HSV-1) anterior uveitis evolving into an acute iris transillumination-like syndrome with secondary pigmentary glaucoma, highlighting diagnostic challenges and treatment considerations. A 61-year-old immunocompetent woman presented with unilateral anterior uveitis characterized by keratic precipitates and mild anterior chamber inflammation. The condition was initially treated with topical and subconjunctival corticosteroids without antiviral therapy.
View Article and Find Full Text PDFJBJS Case Connect
July 2025
Department of Spine Surgery, Ganga Hospital, Coimbatore, India.
Case: A 14-year-old national-level badminton player presented with bilateral L5 pars interarticularis defects with pseudoarthrosis, unresponsive to conservative management. Computed tomography confirmed bilateral pars defect with sclerosed margins without spondylolisthesis or canal compromise. The patient underwent robotic-assisted minimally invasive pars repair augmented with recombinant human bone morphogenetic protein.
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