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Background: Surgery is indicated for symptomatic epiphrenic esophageal diverticula. Based on the features of a case, thoracoscopic or laparoscopic approaches may be used. Epiphrenic diverticula are often associated with esophageal motility disorders, but cases of reflux esophagitis have rarely been reported. In this report, we describe a case of an epiphrenic esophageal diverticulum with reflux esophagitis, which was successfully treated by thoracoscopic diverticulectomy and laparoscopic fundoplication.
Case Presentation: A 69-year-old man visited the hospital with a chief complaint of eructation and hiccup. Upper gastrointestinal endoscopy revealed a diverticulum in the left wall of the esophagus, which was 37-45 cm distal to the incisors. High-resolution manometry (HRM) showed no esophageal motility disorders. Due to the large size of the diverticulum, a thoracoscopic resection of the esophageal diverticulum was performed. Additionally, the patient had reflux esophagitis due to a hiatal hernia. The anti-reflux mechanism would be more impaired during the diverticulectomy; therefore, we decided that anti-reflux surgery should be performed simultaneously. Thoracoscopic esophageal diverticulectomy and laparoscopic Dor fundoplication were performed. The patient had an uncomplicated postoperative course and was discharged on the tenth operative day. He has been symptom-free without acid secretion inhibitors for 21 months after the surgery.
Conclusions: We described a rare case of a large epiphrenic diverticulum with reflux esophagitis. A good surgical outcome was achieved by thoracoscopic resection of the diverticulum and laparoscopic Dor fundoplication.
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http://dx.doi.org/10.1186/s40792-024-01813-0 | DOI Listing |
Curr Opin Gastroenterol
July 2025
Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, USA.
Purpose Of Review: Acid suppression is the mainstay of management of common foregut disorders, including gastroesophageal reflux disease (GERD), peptic ulcer disease and Helicobacter pylori infection. Drawbacks of standard management with proton pump inhibitors (PPIs) include acid lability requiring enteric coating, slow onset of effect, lack of suppression of nocturnal acid breakthrough, and need for administration before meals.
Recent Findings: Potassium-competitive acid blockers (PCABs) are a novel class of acid suppressants that are effective in the management of symptomatic and erosive GERD, peptic ulcer disease and H.
Diabetes Obes Metab
September 2025
Department of Minimally Invasive Surgery, Hernias and Abdominal Wall Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Clinical Research Center for Gastroesophageal Reflux Disease and Bariatric Metabolic Surgery, Research Institute of General and Minimally Invasive Surgery, Ur
Aims: This randomised controlled trial compared the efficacy of modified laparoscopic sleeve gastrectomy with fundoplication (LSGFD) versus standard laparoscopic sleeve gastrectomy (LSG) in achieving weight loss and alleviating gastroesophageal reflux disease (GERD) in patients with obesity.
Materials And Methods: Eighty patients with obesity (body mass index [BMI] ≥27.5 kg/m with comorbidities or ≥32.
Gut Liver
September 2025
Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan.
The Lyon Consensus 2.0, published in 2023, provides an updated diagnostic framework for gastroesophageal reflux disease (GERD), emphasizing objective physiological testing and introducing the concept of "actionable GERD" to guide individualized therapy. This review evaluates the clinical applicability of this framework in Asia, where normative values require regional adaptation.
View Article and Find Full Text PDFIntern Med
September 2025
Second Department of Internal Medicine, Shimane University Faculty of Medicine, Japan.
Objective Reflux esophagitis (RE) is caused by gastroesophageal acid reflux, whereas the heterotopic gastric mucosa (HGM) of the cervical esophagus often shows acid secretion. This study investigated whether an intra-esophageal acidic condition in patients with RE or HGM prevents the occurrence of esophageal candidiasis. Materials We enrolled 5,221 adults (males/females: 3,260/1,961, mean age 54.
View Article and Find Full Text PDFEur J Gastroenterol Hepatol
July 2025
Department of Medicine, King Edward Medical University, Mayo Hospital, Lahore, Pakistan.
Tegoprazan, a novel potassium-competitive acid blocker, has emerged as a potential alternative to proton pump inhibitors (PPIs) for the treatment of erosive esophagitis (EE), especially in light of long-term safety concerns associated with PPIs. This study aimed to assess the efficacy and safety of tegoprazan compared to PPIs in patients with EE. A systematic review and meta-analysis were conducted following preferred reporting items for systematic reviews and meta-analyses guidelines, including three randomized controlled trials with a total of 658 patients diagnosed with EE.
View Article and Find Full Text PDF