Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.2174/0109298673289734231228105444DOI Listing

Publication Analysis

Top Keywords

exploring role
4
role nitric
4
nitric oxide
4
oxide lower
4
lower airway
4
airway diseases
4
diseases insights
4
insights real-world
4
real-world application
4
exploring
1

Similar Publications

Background: Work-related stress is a well-established contributor to mental health decline, particularly in the context of burnout, a state of prolonged exhaustion. Epigenetic clocks, which estimate biological age based on DNA methylation (DNAm) patterns, have been proposed as potential biomarkers of chronic stress and its impact on biological aging and health. However, their role in mediating the relationship between work-related stress, physiological stress markers, and burnout remains unclear.

View Article and Find Full Text PDF

Nuclear receptors (NRs) are a superfamily of ligand-activated transcription factors that regulate gene expression in response to metabolic, hormonal, and environmental signals. These receptors play a critical role in metabolic homeostasis, inflammation, immune function, and disease pathogenesis, positioning them as key therapeutic targets. This review explores the mechanistic roles of NRs such as PPARs, FXR, LXR, and thyroid hormone receptors (THRs) in regulating lipid and glucose metabolism, energy expenditure, cardiovascular health, and neurodegeneration.

View Article and Find Full Text PDF

Experiencing stigmatization during the COVID-19 pandemic: a qualitative study among healthcare workers.

BMC Infect Dis

September 2025

Department Health and Prevention, Institute of Psychology, University of Greifswald, Robert-Blum-Str. 13, Greifswald, 17489, Germany.

Background: Healthcare workers (HCWs) played a crucial role in dealing with the COVID-19 pandemic. In addition to increased workloads, they were confronted with stigmatization due to their work in the health sector.

Methods: Guided by the Health Stigma and Discrimination Framework (HSDF), this study aimed to explore the experiences of stigmatization of HCWs in Germany using semi-structured interviews (N = 34) and investigate effective coping strategies and existing needs in this context.

View Article and Find Full Text PDF

Background: Multi-cancer detection (MCED) blood tests have the potential to screen for early-stage cancers. Understanding how people experience an MCED cancer signal result is vital prior to any future implementation. We explored experiences in a trial context.

View Article and Find Full Text PDF

Obstructive sleep apnea (OSA) is associated with metabolic disorders such as insulin resistance and liver fat accumulation. However, the specific mediating role of liver-related metabolic indicators in this association has not been fully studied. The purpose of this study was to investigate the relationship between Metabolic Score for Insulin Resistance (METS-IR) and OSA, focusing on the mediating effects of liver fat percentage (PLF) and hepatic steatosis index (HSI).

View Article and Find Full Text PDF