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Article Abstract
Therapeutic Level IV . See Instructions for Authors for a complete description of levels of evidence.
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Analysis of polypropylene meshes with embedded silver ions in ventral hernia repair: can they be used in different grades of contamination?
Hernia
September 2025
Unit of Abdominal wall surgery, Department of Digestive Surgery, Hospital Universitari i Poltecnic La Fe, Calle Gabriel Miró 28, puerta 12, Valencia, 46008, Spain.
Background: This study aimed to analyze the outcomes of patients undergoing ventral hernia repair (VHR) with a polypropylene mesh with embedded silver ions (PSM) in the context of different degrees of contamination, compared to standard conventional macroporous polypropylene mesh (PPL).
Methods: From May 2019 to October 2023, a retrospective comparative analysis of patients who underwent elective or urgent VHR with a SilverMesh (PSM group) versus standard macroporous polypropylene mesh (PPL group), based on the Spanish Hernia registry (EVEREG). The exclusion criteria were other PSM indications (groin hernia, prophylaxis) and the use of composite meshes or any material different to PPL.
Electrospun surgical meshes with bioactive coatings for preventing postoperative infections in hernia repair.
Int J Pharm
October 2025
Departamento de Medicina y Especialidades Médicas, Facultad de Medicina y Ciencias de la Salud, Universidad de Alcalá, 28805 Alcalá de Henares, Madrid, Spain; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, 280
Functionalization of hernia repair mesh materials with drug-releasing coatings enables local and controlled therapeutic delivery, offering promising, cutting-edge devices to prevent postoperative infection. In this study, we evaluated in vitro and in vivo two novel antibacterial coatings applied to polypropylene meshes used in surgical hernia repair. Carboxymethylcellulose/polyvinyl alcohol (CMC/PVA) microfibers combined with chlorhexidine (CHX) or rifampicin (RIF) were electrospun on both sides of the mesh, establishing 4 groups: uncoated control; CMC/PVA; CMC/PVA + CHX; CMC/PVA + RIF.
View Article and Find Full Text PDFUse of Prolene Mesh in the Treatment of Traumatic Midface Fractures.
J Long Term Eff Med Implants
July 2025
JSS Dental College & Hospital, Mysuru, Karnataka, India.
Midface fractures constitute a severe medical challenge due to their intricacy, incidence, and socioeconomic implications. The orbit and the maxillary sinus are the most prominent parts of the face and form the most common site of fracture. Reconstruction of these frequently observed fractures is necessary.
View Article and Find Full Text PDFPolypropylene Surgical Mesh Implants for Hernia and Pelvic Floor Disorders: A Materials Performance Perspective.
J Biomed Mater Res A
August 2025
Division of Biology, Chemistry and Materials Science, Center for Devices and Radiological Health, United States Food and Drug Administration, Silver Spring, Maryland, USA.
Surgical meshes are medical devices that were initially designed for hernia repair and later adopted for pelvic floor reconstructive surgeries, including pelvic organ prolapse (POP) and stress urinary incontinence (SUI). Polypropylene (PP) is the most common material for surgical mesh, but others have been used clinically. Complications with PP surgical mesh have been attributed to several factors, including the post-implantation degradation of the surgical mesh materials.
View Article and Find Full Text PDFPurpose: To evaluate the effectiveness of a new format of prophylactic mesh, with a new method of placement.
Methods: Rabbits were randomly distributed into four groups: control rabbits without laparotomy group; sutured rabbits (SR); light-weight mesh rabbits (LWMR); and heavy-weight mesh rabbits (HWMR). The meshes were cut to a size of 10 cm in length by 1 cm in width.