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As a significant geometric feature of 3D point clouds, sharp features play an important role in shape analysis, 3D reconstruction, registration, localization, etc. Current sharp feature detection methods are still sensitive to the quality of the input point cloud, and the detection performance is affected by random noisy points and non-uniform densities. In this paper, using the prior knowledge of geometric features, we propose a Multi-scale Laplace Network (MSL-Net), a new deep-learning-based method based on an intrinsic neighbor shape descriptor, to detect sharp features from 3D point clouds. First, we establish a discrete intrinsic neighborhood of the point cloud based on the Laplacian graph, which reduces the error of local implicit surface estimation. Then, we design a new intrinsic shape descriptor based on the intrinsic neighborhood, combined with enhanced normal extraction and cosine-based field estimation function. Finally, we present the backbone of MSL-Net based on the intrinsic shape descriptor. Benefiting from the intrinsic neighborhood and shape descriptor, our MSL-Net has simple architecture and is capable of establishing accurate feature prediction that satisfies the manifold distribution while avoiding complex intrinsic metric calculations. Extensive experimental results demonstrate that with the multi-scale structure, MSL-Net has a strong analytical ability for local perturbations of point clouds. Compared with state-of-the-art methods, our MSL-Net is more robust and accurate.
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http://dx.doi.org/10.1109/TVCG.2023.3346907 | DOI Listing |
Nat Methods
September 2025
Electron Microscopy Science Technology Platform, The Francis Crick Institute, London, UK.
Volume correlative light and electron microscopy (vCLEM) is a powerful imaging technique that enables the visualization of fluorescently labeled proteins within their ultrastructural context. Currently, vCLEM alignment relies on time-consuming and subjective manual methods. This paper presents CLEM-Reg, an algorithm that automates the three-dimensional alignment of vCLEM datasets by leveraging probabilistic point cloud registration techniques.
View Article and Find Full Text PDFCortex
August 2025
Experimental Psychology and Methods, Universität Leipzig, Leipzig, Germany. Electronic address:
Effects of location- and object-based attention on sensory processing have been mostly studied in isolation leaving the relations between them less well understood. In an EEG experiment, temporal dynamics of location- and object-based attention were investigated with a probabilistic spatial cueing task to test temporal differences between sensory enhancement of two locations in one object. Stimuli consisted of two vertical rectangles/bars filled with a random noise pattern.
View Article and Find Full Text PDFAm J Ophthalmol
September 2025
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Duke-NUS Graduate Medical School, Singapore; Department of Ophthalmology, Emory University School of Medicine, Emory University; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta
Purpose: To characterize the 3D structural phenotypes of the optic nerve head (ONH) in patients with glaucoma, high myopia, and concurrent high myopia and glaucoma, and to evaluate their variations across these conditions.
Design: Retrospective cross-sectional study.
Participants: A total of 685 optical coherence tomography (OCT) scans from 754 subjects of Singapore-Chinese ethnicity, including 256 healthy (H), 94 highly myopic (HM), 227 glaucomatous (G), and 108 highly myopic with glaucoma (HMG) cases METHODS: We segmented the retinal and connective tissue layers from OCT volumes and their boundary edges were converted into 3D point clouds.
Neural Netw
September 2025
School of Automation and Intelligent Sensing, Shanghai Jiao Tong University, Shanghai, 200240, China; Institute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, Shanghai, 200240, China; Institute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, 200240, China.
3D shape defect detection plays an important role in autonomous industrial inspection. However, accurate detection of anomalies remains challenging due to the complexity of multimodal sensor data, especially when both color and structural information are required. In this work, we propose a lightweight inter-modality feature prediction framework that effectively utilizes multimodal fused features from the inputs of RGB, depth and point clouds for efficient 3D shape defect detection.
View Article and Find Full Text PDFPhys Chem Chem Phys
September 2025
Department of Chemistry, Veer Narmad South Gujarat University (VNSGU), Udhna - Magdalla Road, Surat-395007, Gujarat, India.
This work reports the nanoscale micellar formation in single and mixed surfactant systems by combining an amphiphilic graft copolymer, Soluplus® (primary surfactant), blended with other polyoxyethylene (POE)-based nonionic surfactants such as Kolliphor® HS15, Kolliphor® EL, Tween-80, TPGS®, and Pluronics® P123 in an aqueous solution environment. The solution behaviour of these surfactants as a single system were analyzed in a wide range of surfactant concentrations and temperatures. Rheological measurements revealed distinct solution behaviour in the case of Soluplus®, ranging from low-viscosity () and fluid-like behavior at ≤20% w/v to a highly viscous state at ≥90% w/v, where the loss modulus ('') exceeded the storage modulus (').
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