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The use of autoclitics can influence the behavior of individuals making choices when responding to a survey (e.g., checking or unchecking a box). In two studies, we investigated the effects of autoclitics as "nudges" on choice by manipulating different frames (opt-in and opt-out) and default options (i.e., unchecked and checked boxes). Undergraduate students recruited from behavioral science courses engaged with materials in the study. In study 1, we used an online survey at the beginning of the semester offering the choice of whether to enroll in extra-academic activities (i.e., practice tests) available via the online course platform, Blackboard. We randomly assigned students into one of four groups: 1) option to enroll with an unchecked box, 2) option to not enroll with an unchecked box, 3) option to enroll with a checked box, or 4) option to not enroll with a checked box. Results showed that the option to not enroll with an unchecked box produced higher enrollment to receive extra academic activities. In the middle of the semester, we conducted a within-subject arrangement wherein students who initially opted out of receiving activities had the option to accept them following exposure to the negative autoclitic frame. Most of these students opted into receiving activities. In study 2, we replicated the methods of study 1 in Canvas, a different course platform, and obtained similar results. We briefly discuss the implications of a nudge for ethical consent.
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http://dx.doi.org/10.1007/s40616-023-00186-z | DOI Listing |
Cancer Med
September 2025
Department of Pulmonary Medicine, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Background: The prognosis of small-cell lung cancer (SCLC) remains poor, particularly in patients with extensive-stage SCLC. The IMpower133 and CASPIAN trials revealed the efficacy of immune checkpoint inhibitors (ICIs) in extensive-stage SCLC patients with good performance status (PS). The aim of this study was to investigate the efficacy of ICIs in patients with poor PS.
View Article and Find Full Text PDFCirculation
September 2025
Division of Cardiology, Columbia University Irving Medical Center, New York, NY (S.A.P.).
Background: Limited treatment options exist for infrapopliteal disease in patients with chronic limb-threatening ischemia (CLTI), a condition associated with a high risk of limb loss. Interventional management of diseased infrapopliteal vessels with percutaneous transluminal angioplasty (PTA) is associated with high rates of restenosis and reintervention. In the LIFE-BTK trial, the drug-eluting resorbable scaffold (DRS) demonstrated superior 12-month efficacy compared with PTA in a selected CLTI population with predominantly noncomplex, mildly to moderately calcified lesions.
View Article and Find Full Text PDFJ Asthma Allergy
September 2025
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University Kyoto, Kyoto, Japan.
Background And Purpose: Biologics are crucial for severe asthma treatment, but their high costs pose challenges. Omalizumab (OML) is dosed on the basis of patient-specific factors. The purpose of this study is to clarify the clinical characteristics of severe asthmatics who maintain long-term control on omalizumab including healthcare cost considerations.
View Article and Find Full Text PDFLasers Surg Med
September 2025
Department of Dermatology, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Objectives: Post-acne erythema (PAE), a common consequence of acne, is characterized by capillary dilation and erythema, which significantly impact facial aesthetics and quality of life. This study aims to evaluate and compare the efficacy and safety of intense pulsed light (DPL) and 1064 nm Q-switched Nd:YAG laser in treating PAE.
Methods: This prospective, randomized, self-controlled, evaluator-blinded clinical trial compared DPL and 1064 nm Q-switched Nd:YAG laser treatments on one side of the face, with biweekly sessions for 6 weeks.
Clin Rheumatol
September 2025
Immunology Market Access, Johnson & Johnson, Horsham, PA, USA.
Introduction/objective: Oral glucocorticoids (OGC) are conventionally used as first-line treatment for dermatomyositis (DM) and polymyositis (PM). This study evaluated clinical and economic outcomes associated with long-term (LT) OGC use in DM/PM.
Methods: Adults with ≥ 2 medical claims of DM/PM 30‒365 days apart from January 1, 2016, to December 31, 2022, and ≥ 1 diagnosis code of a physician specialty of interest were selected from the MarketScan Commercial and Medicare Supplemental databases.