Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jgg.2023.11.006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Parvin is essential for indirect flight muscle (IFM) performance and Zasp52 localisation to the Z-disc in Drosophila melanogaster.
Cell Tissue Res
September 2025
Department of Life Sciences, Central University of Jharkhand, Cheri-Manatu Campus, Ranchi, Jharkhand, 835222, India.
The integrin-associated proteins (IAPs) function in a tightly regulated and coordinated manner to maintain the complex cytoarchitecture at the myotendinous junctions (MTJs) of Drosophila indirect flight muscles (IFMs). Parvin, a conserved but less explored IAP, forms a ternary complex with ILK and PINCH (the IPP complex). Although the IPP complex is functionally conserved, playing a central role in integrin-mediated adhesion, its individual components may also exert independent roles.
View Article and Find Full Text PDFSpatial Gradient of Axon Terminal Maturation Reveals the Sequential Active Zone Assembly in Adult Mushroom Bodies.
MicroPubl Biol
August 2025
Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi, Japan.
Presynaptic active zones (AZs) form during synaptogenesis and are critical for ensuring precise synaptic transmission. Although much is known about the development of AZs at the neuromuscular junction, their assembly in the central nervous system (CNS) remains incompletely understood. Here, we demonstrate the mushroom body α/β Kenyon cells in young adults in which new AZs are continuously formed, as a novel system to dissect the sequential AZ assembly in the CNS.
View Article and Find Full Text PDFMushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions.
Development
September 2025
Department of Cell Biology, New York University Grossman School of Medicine, 540 First Avenue, New York, NY 10016, USA.
The Drosophila cell adhesion molecule Sidekick is a key component of tricellular adherens junctions in epithelia, and localizes to specific synaptic layers in the optic lobes. Using mutagenesis of endogenous Sidekick, we showed that its enrichment at apical tricellular junctions and its function in cell rearrangement require its fifth and sixth immunoglobulin domains, but not the first four, although these mediate homophilic adhesion of mammalian Sidekick homologues. The C-terminal PDZ-binding motif of Sidekick contributes to localizing both Sidekick and its intracellular binding partner Canoe to tricellular adherens junctions.
View Article and Find Full Text PDFSupracellular actomyosin assemblies: master coordinators of development.
Development
August 2025
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB3 3DY, UK.
Most movement in biological systems is driven by assemblies of actomyosin, be it in the form of sarcomeres in muscles or as actomyosin networks in non-muscle cells. Actomyosin has several key functions within epithelial cells, the cells that will form most of the organs of an animal during development. One such function is to support cellular shape through an actomyosin cortex just underneath the plasma membrane.
View Article and Find Full Text PDFMolecular characterization of major antigens NcSAG1 and NcSRS2.
R Soc Open Sci
August 2025
Laboratorio de Interacciones Hospedero Patogeno, Institut Pasteur de Montevideo, Montevideo, Uruguay.
The SAG1-related sequence (SRS) protein family was initially identified in as glycosyl-phosphatidylinositol-anchored surface antigens. More recently, they have been identified in , the causative agent of neosporosis, a leading cause of bovine abortion worldwide. These proteins are implicated in parasite adhesion to and invasion of host cells, immune response modulation and structural roles in the cyst wall.
View Article and Find Full Text PDF