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http://dx.doi.org/10.1097/TA.0000000000004214 | DOI Listing |
Anal Chem
September 2025
School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Abnormal glycosylation is widespread in cancer, and the overexpression of glycoantigens is a manifestation of glycosylation abnormalities. Tn antigen, sTn antigen, and T antigen are known as tumor-associated glycoantigens, and their expression varies in different tumors or subtypes of the same tumor. Therefore, simultaneous detection of these three glycoantigens is of great significance for the diagnosis of tumors.
View Article and Find Full Text PDFOrg Biomol Chem
September 2025
Department of Chemistry, Indian Institute of Engineering Science and Technology (IIEST), Shibpur, P O- Botanic Garden, Howrah- 711103 (WB), India.
A simple yet efficient method involving a visible-light-induced direct, regioselective chalcogenation of indoloquinoxaline derivatives has been developed. Thiols, disulfides and diselenides were found to be efficient as chalcogenating agents in the presence of Rose Bengal as a photosensitizer. This photoinduced C-H functionalization a cross-dehydrogenative-coupling (CDC) protocol was carried out at ambient temperature under an open-air atmosphere.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
Hefei National Research Center for Physical Sciences at the Microscale, School of Chemistry and Materials Science, State Key Laboratory of Precision and Intelligent Chemistry, National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei, Anhui, 230026, China.
The construction of C─N bonds from simple precursors under ambient conditions is a fundamental challenge in green chemistry, especially when it comes to avoiding energy-intensive protocols. Here, we present a continuous flow photocatalytic platform that enables the efficient coupling of C─N bonds between methanol and ammonia at ambient temperature and pressure. By synergistically engineering a Pd clusters-decorated TiO photocatalyst (1Pd/TiO) and a mass transfer-enhanced gas-liquid-solid Taylor flow reactor, the system achieves a remarkable formamide productivity of 256.
View Article and Find Full Text PDFComput Biol Med
September 2025
Department of Biomedical Engineering, Linköping University, Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden; School of Medical Sciences and Inflammatory Response and Infection Susceptibility Centre (iRiSC), Faculty of Medicine
Functional magnetic resonance imaging (fMRI) is a pivotal tool for mapping neuronal activity in the brain. Traditionally, the observed hemodynamic changes are assumed to reflect the activity of the most common neuronal type: excitatory neurons. In contrast, recent experiments, using optogenetic techniques, suggest that the fMRI-signal could reflect the activity of inhibitory interneurons.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Center for Advanced Jet Engineering Technologies (CaJET), School of Mechanical Engineering, Shandong University, Jinan 250061, China.
Solar-driven interfacial evaporation technology represents an innovative and high-efficiency desalination approach. This technology plays a crucial role in relieving the shortage of worldwide freshwater resources. However, the interfacial evaporator still faces great challenges in terms of high efficiency and ensuring long-term evaporation stability, among other aspects.
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