Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

https://bit.ly/3PLNTXC.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641575PMC
http://dx.doi.org/10.1183/23120541.00138-2023DOI Listing

Publication Analysis

Top Keywords

compartment-specific protein
4
protein interactions
4
interactions beryllium
4
beryllium lung
4
lung disease
4
disease https//bitly/3plntxc
4
compartment-specific
1
interactions
1
beryllium
1
lung
1

Similar Publications

Background/aim: Chronic airway diseases, including chronic obstructive pulmonary disease (COPD), asthma, and asthma COPD overlap (ACO), are characterized by complex inflammatory processes in which Activin A-a key member of the TGF-β superfamily-is implicated. Although its role in the stable state of these diseases has been extensively studied, data regarding its involvement during exacerbations remain limited. Our objective was to investigate the dynamics of Activin A in sputum and serum during acute exacerbations and subsequent convalescence in patients with chronic airway diseases.

View Article and Find Full Text PDF

Background: Respiratory syncytial virus (RSV) bronchiolitis is a leading cause of lower respiratory tract infections in children under two years of age. NF-κB is a key transcription factor in antiviral and inflammatory responses. This study investigates the expression of NF-κB mRNA in both blood and buccal swab samples of pediatric patients hospitalized for RSV bronchiolitis, comparing levels at admission and discharge.

View Article and Find Full Text PDF

T lymphocytes in human skin play essential roles in immune surveillance and tissue homeostasis, with distinct populations residing in the epidermal and dermal compartments. To characterize the molecular basis of their compartmentalized functional specialization, we performed proteomic analysis of total T cell populations isolated from healthy human skin, combining flow cytometry and liquid chromatography-tandem mass spectrometry. We quantified 5985 proteins across epidermal and dermal T cell populations, identifying 2177 significantly differentially expressed proteins (FDR < 0.

View Article and Find Full Text PDF

Background: Persistent low-grade inflammation has been hypothesized as a possible key contributor to polycystic ovary syndrome pathophysiology through associative studies. Since immune cells within the ovarian follicle-the central site of PCOS dysfunction-play pivotal roles in immune defense and regulation of ovulation, establishing a definitive cellular map of normal and PCOS-affected follicular immune composition is essential.

Method: This is a prospective cohort study of women with PCOS (Rotterdam criteria) and controls undergoing fertilization (IVF).

View Article and Find Full Text PDF

Specific viral antibodies associate with anti-NMDAR encephalitis after herpes simplex encephalitis.

Brain Behav Immun

August 2025

Institute for Cell Engineering, Division of Immunology, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA. Electronic address:

Herpes simplex encephalitis (HSE) patients may develop secondary anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis (NMDARE), associated with worsened long-term neurological outcome. Immunosuppressive treatment can limit NMDAR autoantibody-mediated pathology, but early predictive biomarkers for the risk of NMDARE are lacking. In a multicenter study, we performed unbiased antibody reactome profiling using Phage ImmunoPrecipitation Sequencing (PhIP-Seq).

View Article and Find Full Text PDF